How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions

AM Bruger, A Dorhoi, G Esendagli… - Cancer Immunology …, 2019 - Springer
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of mononuclear and
polymorphonuclear myeloid cells, which are present at very low numbers in healthy …

[HTML][HTML] Positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging of macrophages in large vessel vasculitis: current …

WF Jiemy, P Heeringa, JAAM Kamps… - Autoimmunity …, 2018 - Elsevier
Macrophages are key players in the pathogenesis of large-vessel vasculitis (LVV) and may
serve as a target for diagnostic imaging of LVV. The radiotracer, 18 F-FDG has proven to be …

[HTML][HTML] Protective Effects of Phyllanthus amarus Against Lipopolysaccharide-Induced Neuroinflammation and Cognitive Impairment in Rats

A Alagan, I Jantan, E Kumolosasi, S Ogawa… - Frontiers in …, 2019 - frontiersin.org
Background: Phyllanthus amarus (PA) is widely studied for its hepatoprotective properties
but has recently received increasing attention due to its diverse anti-inflammatory effects …

MR/SPECT Imaging Guided Photothermal Therapy of Tumor-Targeting Fe@Fe3O4 Nanoparticles in Vivo with Low Mononuclear Phagocyte Uptake

J Wang, H Zhao, Z Zhou, P Zhou, Y Yan… - … applied materials & …, 2016 - ACS Publications
The 125I-c (RGDyK) peptide PEGylated Fe@ Fe3O4 nanoparticles (125I-RGD-PEG-MNPs)
with the average hydrodynamic diameter of∼ 40 nm as a novel multifunctional platform …

[HTML][HTML] PET imaging of macrophages in cardiovascular diseases

X Li, ZT Rosenkrans, J Wang, W Cai - American journal of …, 2020 - ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) have been the leading cause of death in United States.
While tremendous progress has been made for treating CVDs over the year, the high …

Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress

BH Li, FP He, X Yang, YW Chen, JG Fan - Translational Research, 2017 - Elsevier
The rapidly increasing prevalence of nonalcoholic fatty liver disease (NAFLD) has become
one of the major public health threats in China and worldwide. However, during the …

Targeting infiltrating myeloid cells in gastric cancer using a pretargeted imaging strategy based on bio-orthogonal diels–alder click chemistry and comparison with …

Y Zhang, Q Lin, T Wang, D Shi, Z Fu, Z Si… - Molecular …, 2021 - ACS Publications
Gastric cancer (GC) is a common cancer worldwide, with high incidence and mortality rates.
Therefore, early and precise diagnosis is critical to improving GC prognosis. Tumor …

[HTML][HTML] It's time to shift the paradigm: translation and clinical application of non-αvβ3 integrin targeting radiopharmaceuticals

S Kossatz, AJ Beer, J Notni - Cancers, 2021 - mdpi.com
Simple Summary Cancer cells often present a different set of proteins on their surface than
normal cells. This also applies to integrins, a class of 24 cell surface receptors which mainly …

[HTML][HTML] Molecular imaging for evaluation of synovitis associated with osteoarthritis: a narrative review

K Lee, S Niku, SJ Koo, E Belezzuoli… - Arthritis Research & …, 2024 - Springer
Recent evidence highlights the role of low-grade synovial inflammation in the progression of
osteoarthritis (OA). Inflamed synovium of OA joints detected by imaging modalities are …

Antibody‐Based Tracers for PET/SPECT Imaging of Chronic Inflammatory Diseases

HJ Lee, EB Ehlerding, W Cai - ChemBioChem, 2019 - Wiley Online Library
Chronic inflammatory diseases are often progressive, resulting not only in physical damage
to patients but also social and economic burdens, making early diagnosis of them critical …