How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions
AM Bruger, A Dorhoi, G Esendagli… - Cancer Immunology …, 2019 - Springer
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of mononuclear and
polymorphonuclear myeloid cells, which are present at very low numbers in healthy …
polymorphonuclear myeloid cells, which are present at very low numbers in healthy …
[HTML][HTML] Positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging of macrophages in large vessel vasculitis: current …
Macrophages are key players in the pathogenesis of large-vessel vasculitis (LVV) and may
serve as a target for diagnostic imaging of LVV. The radiotracer, 18 F-FDG has proven to be …
serve as a target for diagnostic imaging of LVV. The radiotracer, 18 F-FDG has proven to be …
[HTML][HTML] Protective Effects of Phyllanthus amarus Against Lipopolysaccharide-Induced Neuroinflammation and Cognitive Impairment in Rats
Background: Phyllanthus amarus (PA) is widely studied for its hepatoprotective properties
but has recently received increasing attention due to its diverse anti-inflammatory effects …
but has recently received increasing attention due to its diverse anti-inflammatory effects …
MR/SPECT Imaging Guided Photothermal Therapy of Tumor-Targeting Fe@Fe3O4 Nanoparticles in Vivo with Low Mononuclear Phagocyte Uptake
The 125I-c (RGDyK) peptide PEGylated Fe@ Fe3O4 nanoparticles (125I-RGD-PEG-MNPs)
with the average hydrodynamic diameter of∼ 40 nm as a novel multifunctional platform …
with the average hydrodynamic diameter of∼ 40 nm as a novel multifunctional platform …
[HTML][HTML] PET imaging of macrophages in cardiovascular diseases
Cardiovascular diseases (CVDs) have been the leading cause of death in United States.
While tremendous progress has been made for treating CVDs over the year, the high …
While tremendous progress has been made for treating CVDs over the year, the high …
Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress
BH Li, FP He, X Yang, YW Chen, JG Fan - Translational Research, 2017 - Elsevier
The rapidly increasing prevalence of nonalcoholic fatty liver disease (NAFLD) has become
one of the major public health threats in China and worldwide. However, during the …
one of the major public health threats in China and worldwide. However, during the …
Targeting infiltrating myeloid cells in gastric cancer using a pretargeted imaging strategy based on bio-orthogonal diels–alder click chemistry and comparison with …
Y Zhang, Q Lin, T Wang, D Shi, Z Fu, Z Si… - Molecular …, 2021 - ACS Publications
Gastric cancer (GC) is a common cancer worldwide, with high incidence and mortality rates.
Therefore, early and precise diagnosis is critical to improving GC prognosis. Tumor …
Therefore, early and precise diagnosis is critical to improving GC prognosis. Tumor …
[HTML][HTML] It's time to shift the paradigm: translation and clinical application of non-αvβ3 integrin targeting radiopharmaceuticals
Simple Summary Cancer cells often present a different set of proteins on their surface than
normal cells. This also applies to integrins, a class of 24 cell surface receptors which mainly …
normal cells. This also applies to integrins, a class of 24 cell surface receptors which mainly …
[HTML][HTML] Molecular imaging for evaluation of synovitis associated with osteoarthritis: a narrative review
K Lee, S Niku, SJ Koo, E Belezzuoli… - Arthritis Research & …, 2024 - Springer
Recent evidence highlights the role of low-grade synovial inflammation in the progression of
osteoarthritis (OA). Inflamed synovium of OA joints detected by imaging modalities are …
osteoarthritis (OA). Inflamed synovium of OA joints detected by imaging modalities are …
Antibody‐Based Tracers for PET/SPECT Imaging of Chronic Inflammatory Diseases
HJ Lee, EB Ehlerding, W Cai - ChemBioChem, 2019 - Wiley Online Library
Chronic inflammatory diseases are often progressive, resulting not only in physical damage
to patients but also social and economic burdens, making early diagnosis of them critical …
to patients but also social and economic burdens, making early diagnosis of them critical …