[HTML][HTML] Molecular targeted therapy of cancer: The progress and future prospect

X Ke, L Shen - Frontiers in Laboratory Medicine, 2017 - Elsevier
Cancer has become a major public health problem worldwide. Researches focus on the
new approaches for cancer treatments that involve the specific targets of the cancer disease …

203/212Pb theranostic radiopharmaceuticals for image-guided radionuclide therapy for cancer

M Li, EA Sagastume, D Lee, D McAlister… - Current medicinal …, 2020 - ingentaconnect.com
Receptor-targeted image-guided Radionuclide Therapy (TRT) is increasingly recognized as
a promising approach to cancer treatment. In particular, the potential for clinical translation of …

[HTML][HTML] An Overview of In Vitro Assays of 64Cu-, 68Ga-, 125I-, and 99mTc-Labelled Radiopharmaceuticals Using Radiometric Counters in the Era of …

V Benfante, A Stefano, M Ali, R Laudicella, W Arancio… - Diagnostics, 2023 - mdpi.com
Radionuclides are unstable isotopes that mainly emit alpha (α), beta (β) or gamma (γ)
radiation through radiation decay. Therefore, they are used in the biomedical field to label …

Clinical applications of radiolabeled peptides for PET

IM Jackson, PJH Scott, S Thompson - Seminars in Nuclear Medicine, 2017 - Elsevier
Radiolabeled peptides are a valuable class of radiotracer that occupies the space between
small molecules and large biologics, and are able to exploit the advantages of both classes …

Automated cassette-based production of high specific activity [203/212Pb] peptide-based theranostic radiopharmaceuticals for image-guided radionuclide therapy for …

M Li, X Zhang, TP Quinn, D Lee, D Liu, F Kunkel… - Applied radiation and …, 2017 - Elsevier
A method for preparation of Pb-212 and Pb-203 labeled chelator-modified peptide-based
radiopharmaceuticals for cancer imaging and radionuclide therapy has been developed and …

Long-term results of a comparative PET/CT and PET/MRI study of 11C-acetate and 18F-fluorocholine for restaging of early recurrent prostate cancer

G Lamanna, C Tabouret-Viaud, O Rager… - Clinical Nuclear …, 2017 - journals.lww.com
Purpose The aims of this study were to assess the intraindividual performance of 18 F-
fluorocholine (FCH) and 11 C-acetate (ACE) PET studies for restaging of recurrent prostate …

[HTML][HTML] Non-viral suicide gene therapy: Cytosine deaminase gene directed by VEGF promoter and 5-fluorocytosine as a gene directed enzyme/prodrug system in …

M Emamian, A Abbaspour, T Shahani, A Biglari… - Drug …, 2021 - thieme-connect.com
The present study investigated the potential of vascular endothelial growth factor (VEGF)
promoter to derive cytosine deaminase (CD) transfected by polyamidoamine (G4-PAMAM) …

Preparation and clinical translation of 99m Tc-PSMA-11 for SPECT imaging of prostate cancer

K Vats, K Agrawal, R Sharma, HD Sarma, D Satpati… - …, 2019 - pubs.rsc.org
This study explores the feasibility of radiolabeling the HBED-CC-PSMA (PSMA-11) ligand
with Tc-99m for SPECT imaging of prostate cancer patients. 68Ga-HBED-CC-PSMA (PSMA …

Molecular processes exploited as drug targets for cancer chemotherapy

SP Gupta, A Sharma, VM Patil - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Cancer is an uncontrolled malignant tumor growth taking place in any tissue of the body and
attains complex diversity which makes it difficult for oncologists to choose therapeutics. The …

[PDF][PDF] Radiotheranostics in prostate cancer: introduction and overview

H Jadvar - Journal of Nuclear Medicine, 2016 - Soc Nuclear Med
Medicine focuses on the current state of affairs and outlook for the use of molecular imaging
and targeted radionuclide therapy in prostate cancer. The recent strides in understanding …