Point-of-care diagnostics: recent developments in a connected age

S Nayak, NR Blumenfeld, T Laksanasopin… - Analytical …, 2017 - ACS Publications
The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …

Real-time optoacoustic tracking of single moving micro-objects in deep phantom and ex vivo tissues

A Aziz, M Medina-Sánchez, J Claussen… - Nano letters, 2019 - ACS Publications
Medical imaging plays an important role in diagnosis and treatment of multiple diseases. It is
a field which seeks for improved sensitivity and spatiotemporal resolution to allow the …

Sample preparation techniques for radiometabolite analysis of positron emission tomography radioligands; trends, progress, limitations and future prospects

MM Moein, R Nakao, N Amini, M Abdel-Rehim… - TrAC Trends in …, 2019 - Elsevier
Radiometabolite corrected arterial plasma input function is essential for quantitative
measurement of the brain binding of positron emitting radioligands and drugs that have no …

Real‐time IR tracking of single reflective micromotors through scattering tissues

A Aziz, M Medina‐Sánchez… - Advanced Functional …, 2019 - Wiley Online Library
Medical micromotors have the potential to lead to a paradigm shift in future biomedicine, as
they may perform active drug delivery, microsurgery, tissue engineering, or assisted …

[HTML][HTML] Enhanced extraction of blood and tissue time-activity curves in cardiac mouse FDG PET imaging by means of constrained nonnegative matrix factorization

O Sarrhini, P D'Orléans-Juste, JA Rousseau… - International Journal of …, 2023 - hindawi.com
We propose an enhanced method to accurately retrieve time-activity curves (TACs) of blood
and tissue from dynamic 2-deoxy-2-[18 F] fluoro-D-glucose ([18 F] FDG) positron emission …

Microfluidic radiobioassays: a radiometric detection tool for understanding cellular physiology and pharmacokinetics

Z Liu, X Lan - Lab on a Chip, 2019 - pubs.rsc.org
The investigation of molecular uptake and its kinetics in cells is valuable for understanding
the cellular physiological status, the observation of drug interventions, and the development …

[HTML][HTML] Imaging technologies for cerebral pharmacokinetic studies: progress and perspectives

W Ban, Y You, Z Yang - Biomedicines, 2022 - mdpi.com
Pharmacokinetic assessment of drug disposition processes in vivo is critical in predicting
pharmacodynamics and toxicology to reduce the risk of inappropriate drug development …

A mini-panel PET scanner-based microfluidic radiobioassay system allowing high-throughput imaging of real-time cellular pharmacokinetics

Z Liu, P Zhang, H Ji, Y Long, B Jing, L Wan, D Xi, R An… - Lab on a Chip, 2020 - pubs.rsc.org
On-chip radiometric detection of biological samples using radiotracers has become an
emerging research field known as microfluidic radiobioassays. Performing parallel …

[HTML][HTML] Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography

S de Scals, LM Fraile, JM Udías, L Martínez Cortés… - EJNMMI physics, 2024 - Springer
Pharmacokinetic positron emission tomography (PET) studies rely on the measurement of
the arterial input function (AIF), which represents the time-activity curve of the radiotracer …

[HTML][HTML] Development of a blood sample detector for multi-tracer positron emission tomography using gamma spectroscopy

C Velasco, A Mota-Cobián, J Mateo, S España - EJNMMI physics, 2019 - Springer
Background Multi-tracer positron emission tomography (PET) imaging can be accomplished
by applying multi-tracer compartment modeling. Recently, a method has been proposed in …