Clinical applications of small-molecule PET radiotracers: current progress and future outlook
AL Vāvere, PJH Scott - Seminars in Nuclear Medicine, 2017 - Elsevier
Radiotracers, or radiopharmaceuticals, are bioactive molecules tagged with a radionuclide
used for diagnostic imaging or radiotherapy and, when a positron-emitting radionuclide is …
used for diagnostic imaging or radiotherapy and, when a positron-emitting radionuclide is …
Bisoprolol therapy does not reduce right ventricular sympathetic activity in pulmonary arterial hypertension patients
MT Rijnierse, JA Groeneveldt… - Pulmonary …, 2020 - journals.sagepub.com
Right ventricular (RV) function and autonomic dysfunction are important determinants of
morbidity and mortality in patients with pulmonary arterial hypertension (PAH). Although …
morbidity and mortality in patients with pulmonary arterial hypertension (PAH). Although …
[HTML][HTML] [11C]mHED PET follows a two-tissue compartment model in mouse myocardium with norepinephrine transporter (NET)-dependent uptake, while [18F] …
Purpose Clinical positron emission tomography (PET) imaging of the presynaptic
norepinephrine transporter (NET) function provides valuable diagnostic information on …
norepinephrine transporter (NET) function provides valuable diagnostic information on …
Reproducible quantification of regional sympathetic denervation with [11C] meta-hydroxyephedrine PET imaging
JZ Wang, JB Moody, N Kaps, D Britt, A Lavallee… - Journal of Nuclear …, 2021 - Elsevier
Background Regional cardiac sympathetic denervation is predictive of sudden cardiac arrest
in patients with ischemic cardiomyopathy. The reproducibility of denervation scores between …
in patients with ischemic cardiomyopathy. The reproducibility of denervation scores between …
Does quantification of [11C] meta-hydroxyephedrine and [13N] ammonia kinetics improve risk stratification in ischemic cardiomyopathy
JZ Wang, JGE Zelt, N Kaps, A Lavallee… - Journal of Nuclear …, 2022 - Elsevier
Background In ischemic cardiomyopathy patients, cardiac sympathetic nervous system
dysfunction is a predictor of sudden cardiac arrest (SCA). This study compared abnormal …
dysfunction is a predictor of sudden cardiac arrest (SCA). This study compared abnormal …
Pharmacological and metabolic parameters of [18F]flubrobenguane in clinical imaging populations
Background Cardiac sympathetic nervous system molecular imaging has demonstrated
prognostic value. Compared with meta-[11C] hydroxyephedrine,[18F] flubrobenguane …
prognostic value. Compared with meta-[11C] hydroxyephedrine,[18F] flubrobenguane …
Automatic segmentation of carotid arteries using Independent Component Analysis for quantitative brain PET
L Vasbinder - 2023 - fse.studenttheses.ub.rug.nl
Accurate estimation of a plasma input function is crucial for quantitative brain PET. The gold
standard to obtain the input function is arterial blood sampling, but this procedure is complex …
standard to obtain the input function is arterial blood sampling, but this procedure is complex …
Assessment of myocardial sympathetic innervation by PET in patients with heart failure: a review of the most recent advances and future perspectives
CE Popescu, M Cuzzocrea, L Monaco… - Clinical and Translational …, 2018 - Springer
Purpose Life-threatening ventricular arrhythmias (VA) are a major cause of death in patients
with congestive heart failure (HF). Among various factors, the sympathetic nervous system …
with congestive heart failure (HF). Among various factors, the sympathetic nervous system …
Imaging of the cardiac sympathetic nervous system has potential value in the evaluation of patients with heart failure with preserved ejection fraction
NE Boutagy, AJ Sinusas - Journal of Nuclear Medicine, 2017 - Soc Nuclear Med
Heart failure (HF) is a major public health problem that affects more than 5.8 million people
in the United States and 23 million people worldwide (1). HF is a clinical syndrome, rather …
in the United States and 23 million people worldwide (1). HF is a clinical syndrome, rather …
Myocardial innervation
M Schwaiger, AF Jacobson, A Saraste, J Narula… - Atlas of nuclear …, 2021 - Springer
An important target for cardiac molecular imaging is the autonomic nervous system, which
exerts both stimulatory (primarily via sympathetic fibers) and inhibitory (primarily via …
exerts both stimulatory (primarily via sympathetic fibers) and inhibitory (primarily via …