Mechanism of action of ribosomally synthesized and post-translationally modified peptides
C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …
product class that has undergone significant expansion due to the rapid growth in genome …
Mechanistic understanding of lanthipeptide biosynthetic enzymes
Lanthipeptides are ribosomally synthesized and post-translationally modified peptides
(RiPPs) that display a wide variety of biological activities, from antimicrobial to antiallodynic …
(RiPPs) that display a wide variety of biological activities, from antimicrobial to antiallodynic …
Guidelines for evaluating myocardial cell death
Cell death is a fundamental process in cardiac pathologies. Recent studies have revealed
multiple forms of cell death, and several of them have been demonstrated to underlie …
multiple forms of cell death, and several of them have been demonstrated to underlie …
Metformin as a radiation modifier; implications to normal tissue protection and tumor sensitization
Background: Nowadays, ionizing radiation is used for several applications in medicine,
industry, agriculture, and nuclear power generation. Besides the beneficial roles of ionizing …
industry, agriculture, and nuclear power generation. Besides the beneficial roles of ionizing …
[HTML][HTML] Promising biomarkers of radiation-induced lung injury: a review
X Liu, C Shao, J Fu - Biomedicines, 2021 - mdpi.com
Radiation-induced lung injury (RILI) is one of the main dose-limiting side effects in patients
with thoracic cancer during radiotherapy. No reliable predictors or accurate risk models are …
with thoracic cancer during radiotherapy. No reliable predictors or accurate risk models are …
Lung tissue extracellular matrix‐derived hydrogels protect against radiation‐induced lung injury by suppressing epithelial–mesenchymal transition
J Zhou, P Wu, H Sun, H Zhou… - Journal of Cellular …, 2020 - Wiley Online Library
This study aimed to examine whether lung tissue extracellular matrix (ECM) hydrogels have
protective effects on radiation‐induced lung injury (RILI). The cytocompatibility and …
protective effects on radiation‐induced lung injury (RILI). The cytocompatibility and …
The time course of radiation-induced lung injury in a nonhuman primate model of partial-body irradiation with minimal bone marrow sparing: clinical and radiographic …
TJ MacVittie, AM Farese, GA Parker… - Health Physics, 2019 - journals.lww.com
The primary objectives of two companion manuscripts were to assess the natural history of
delayed radiation-induced lung injury in a nonhuman primate model of acute high-dose …
delayed radiation-induced lung injury in a nonhuman primate model of acute high-dose …
Phosphatidylethanolamine targeting for cell death imaging in early treatment response evaluation and disease diagnosis
F Elvas, S Stroobants, L Wyffels - Apoptosis, 2017 - Springer
Phosphatidylethanolamine (PE) is one of the most abundant phospholipids in mammalian
plasma membranes. In healthy cells, PE resides predominantly in the inner leaflet of the cell …
plasma membranes. In healthy cells, PE resides predominantly in the inner leaflet of the cell …
Development of biomarkers for radiation biodosimetry and medical countermeasures research: Current status, utility, and regulatory pathways
MM Satyamitra, AL DiCarlo, BA Hollingsworth… - 2022 - meridian.allenpress.com
Biomarkers are important indicators of biological processes in health or disease. For this
reason, they play a critical role in advanced development of radiation biodosimetry tools and …
reason, they play a critical role in advanced development of radiation biodosimetry tools and …
A trans-agency workshop on the pathophysiology of radiation-induced lung injury
DR Cassatt, A Gorovets, B Karimi-Shah, R Roberts… - 2022 - meridian.allenpress.com
Research and development of medical countermeasures (MCMs) for radiation-induced lung
injury relies on the availability of animal models with well-characterized pathophysiology …
injury relies on the availability of animal models with well-characterized pathophysiology …