Click chemistry: a transformative technology in nuclear medicine
Abstract The 2022 Nobel Prize in Chemistry was awarded to Professors K. Barry Sharpless,
Morten Meldal and Carolyn Bertozzi for their pioneering roles in the advent of click …
Morten Meldal and Carolyn Bertozzi for their pioneering roles in the advent of click …
Click chemistry and radiochemistry: the first 10 years
JP Meyer, P Adumeau, JS Lewis… - Bioconjugate …, 2016 - ACS Publications
The advent of click chemistry has had a profound influence on almost all branches of
chemical science. This is particularly true of radiochemistry and the synthesis of agents for …
chemical science. This is particularly true of radiochemistry and the synthesis of agents for …
[HTML][HTML] Somatostatin receptor PET ligands-the next generation for clinical practice
Somatostatin receptors (SSTRs) are variably expressed by a variety of malignancies. Using
radiolabeled somatostatin analogs (SSAs), the presence of SSTRs on tumor cells may be …
radiolabeled somatostatin analogs (SSAs), the presence of SSTRs on tumor cells may be …
[HTML][HTML] The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules
SJ Archibald, L Allott - EJNMMI radiopharmacy and chemistry, 2021 - Springer
Abstract The aluminium-[18F] fluoride ([18F] AlF) radiolabelling method combines the
favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal …
favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal …
Multiplexed imaging for diagnosis and therapy
Complex molecular and metabolic phenotypes depict cancers as a constellation of different
diseases with common themes. Precision imaging of such phenotypes requires flexible and …
diseases with common themes. Precision imaging of such phenotypes requires flexible and …
[18F]AlF-NOTA-octreotide PET imaging: biodistribution, dosimetry and first comparison with [68Ga]Ga-DOTATATE in neuroendocrine tumour patients
Purpose The widespread use of gallium-68-labelled somatostatin analogue (SSA) PET, the
current standard for somatostatin receptor (SSTR) imaging, is limited by practical and …
current standard for somatostatin receptor (SSTR) imaging, is limited by practical and …
Recent advances in bioorthogonal click chemistry for enhanced PET and SPECT radiochemistry
X Zhong, J Yan, X Ding, C Su, Y Xu… - Bioconjugate …, 2023 - ACS Publications
Due to their high reaction rate and reliable selectivity, bioorthogonal click reactions have
been extensively investigated in numerous research fields, such as nanotechnology, drug …
been extensively investigated in numerous research fields, such as nanotechnology, drug …
Somatostatin receptor PET/MR imaging of inflammation in patients with large vessel vasculitis and atherosclerosis
Background Assessing inflammatory disease activity in large vessel vasculitis (LVV) can be
challenging by conventional measures. Objectives We aimed to investigate somatostatin …
challenging by conventional measures. Objectives We aimed to investigate somatostatin …
Clinical application of 18F-AlF-NOTA-octreotide PET/CT in combination with 18F-FDG PET/CT for imaging neuroendocrine neoplasms
T Long, N Yang, M Zhou, D Chen, Y Li, J Li… - Clinical nuclear …, 2019 - journals.lww.com
Objectives The study is to evaluate biodistribution, dosimetry, safety, and clinical usefulness
of 18 F-AlF-NOTA-octreotide (18 F-OC) PET/CT in combination with 18 F-FDG PET/CT for …
of 18 F-AlF-NOTA-octreotide (18 F-OC) PET/CT in combination with 18 F-FDG PET/CT for …
[HTML][HTML] Radiolabelled peptides for positron emission tomography and endoradiotherapy in oncology
C Rangger, R Haubner - Pharmaceuticals, 2020 - mdpi.com
This review deals with the development of peptide-based radiopharmaceuticals for the use
with positron emission tomography and peptide receptor radiotherapy. It discusses the pros …
with positron emission tomography and peptide receptor radiotherapy. It discusses the pros …