[HTML][HTML] Auger electrons for cancer therapy–a review

A Ku, VJ Facca, Z Cai, RM Reilly - EJNMMI radiopharmacy and chemistry, 2019 - Springer
Abstract Background Auger electrons (AEs) are very low energy electrons that are emitted
by radionuclides that decay by electron capture (eg 111 In, 67 Ga, 99m Tc, 195m Pt, 125 I …

Tumor target amplification: implications for nano drug delivery systems

K Seidi, HA Neubauer, R Moriggl… - Journal of controlled …, 2018 - Elsevier
Tumor cells overexpress surface markers which are absent from normal cells. These tumor-
restricted antigenic signatures are a fundamental basis for distinguishing on-target from off …

Monoclonal antibodies for the treatment of cancer

JT Pento - Anticancer research, 2017 - ar.iiarjournals.org
The ability of cancer cells to evade the immune system is one of the most deadly
characteristics of the majority of malignant tumours. Accordingly, the recent development of …

Theranostic approach in breast cancer: a treasured tailor for future oncology

N Jokar, I Velikyan, H Ahmadzadehfar… - Clinical Nuclear …, 2021 - journals.lww.com
Breast cancer is the most frequent invasive malignancy and the second major cause of
cancer death in female subjects mostly due to the considerable diagnostic delay and failure …

[HTML][HTML] Perspectives on metals-based radioimmunotherapy (RIT): moving forward

JM White, FE Escorcia, NT Viola - Theranostics, 2021 - ncbi.nlm.nih.gov
Radioimmunotherapy (RIT) is FDA-approved for the clinical management of liquid
malignancies, however, its use for solid malignancies remains a challenge. The putative …

Targeting HER2 in nuclear medicine for imaging and therapy

AVF Massicano, BV Marquez-Nostra… - Molecular …, 2018 - journals.sagepub.com
Since its discovery, the human epidermal growth factor 2 (HER2) has been extensively
studied. Presently, there are 2 standard diagnostic techniques to assess HER2 status in …

[HTML][HTML] Current status of contemporary diagnostic radiotracers in the management of breast cancer: first steps toward theranostic applications

R Altena, A Tzortzakakis, S Af Burén, TA Tran… - EJNMMI research, 2023 - Springer
Background Expanding therapeutic possibilities have improved disease-related prospects
for breast cancer patients. Pathological analysis on a tumor biopsy is the current reference …

Modulation of glutathione promotes apoptosis in triple‐negative breast cancer cells

ATJ Vogg, N Drude, FM Mottaghy… - The FASEB …, 2018 - Wiley Online Library
Triple‐negative breast cancer has an extremely high rate of relapse. This is particularly due
to the existence and survival of cancer stem cells (CSCs) characterized by increased …

[HTML][HTML] Molecular imaging of HER2 receptor: Targeting HER2 for imaging and therapy in nuclear medicine

D Miladinova - Frontiers in molecular biosciences, 2023 - frontiersin.org
Targeting HER 2 for imaging and therapy in nuclear medicine has been used with a special
emphasis on developing more powerful radiopharmaceuticals. Zirconium-89 plays an …

ImmunoPET and near-infrared fluorescence imaging of pancreatic cancer with a dual-labeled bispecific antibody fragment

H Luo, CG England, S Goel, SA Graves… - Molecular …, 2017 - ACS Publications
Dual-targeted imaging agents have shown improved targeting efficiencies in comparison to
single-targeted entities. The purpose of this study was to quantitatively assess the tumor …