[HTML][HTML] 11C- and 18F-Radiotracers for In Vivo Imaging of the Dopamine System: Past, Present and Future

MR Kilbourn - Biomedicines, 2021 - mdpi.com
The applications of positron emission tomography (PET) imaging to study brain
biochemistry, and in particular the aspects of dopamine neurotransmission, have grown …

Biotransformation of natural hydroxycinnamic acids by gut microbiota from normal and cerebral ischemia-reperfusion injured rats: a comparative study

H Shen, X Tong, J Yang, L Yu, H Zhou, Y Wang, Y He… - Food & function, 2020 - pubs.rsc.org
Hydroxycinnamic acids (HAs) are widely spread in food and herbal medicines. The
bioavailability of HAs largely depends on the absorption and metabolism in enterohepatic …

Striatal serotonin transporter gain-of-function in L-DOPA-treated, hemi-parkinsonian rats

MMC Mazza, A Centner, DF Werner, C Bishop - Brain Research, 2023 - Elsevier
L-DOPA is the standard treatment for Parkinson's disease (PD), but chronic treatment
typically leads to L-DOPA-induced dyskinesia (LID). LID involves a complex interaction …

PET imaging of mitochondrial complex I with 18F-BCPP-EF in the brains of MPTP-treated monkeys

H Tsukada, M Kanazawa, H Ohba… - Journal of Nuclear …, 2016 - Soc Nuclear Med
18F-BCPP-EF was applied to assess mitochondrial complex I (MC-I) activity in the brains of
Parkinson disease model monkeys prepared by 1-methyl-4-phenyl-1, 2, 3, 6 …

Comparative assessment of 6‐[18F]fluoro‐L‐m‐tyrosine and 6‐[18F]fluoro‐L‐dopa to evaluate dopaminergic presynaptic integrity in a Parkinson's disease rat …

G Becker, MA Bahri, A Michel, F Hustadt… - Journal of …, 2017 - Wiley Online Library
Because of the progressive loss of nigro‐striatal dopaminergic terminals in Parkinson's
disease (PD), in vivo quantitative imaging of dopamine (DA) containing neurons in animal …

[HTML][HTML] Tyrosinase mediated oxidative functionalization in the synthesis of DOPA-derived peptidomimetics with anti-Parkinson activity

BM Bizzarri, A Martini, F Serafini, D Aversa… - RSC …, 2017 - pubs.rsc.org
DOPA-derived peptidomimetics are an attractive therapeutic tool for the treatment of
Parkinson's disease. Compounds with unusual O–C and N–C covalent bonds between …

Effect of MPTP on serotonergic neuronal systems and mitochondrial complex I activity in the living brain: a PET study on conscious rhesus monkeys

M Kanazawa, H Ohba, S Nishiyama… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The objective of the present PET study was to compare the effect of 1-methyl-4-phenyl-1, 2,
3, 6-tetrahydropyridine (MPTP) on serotonergic neuronal systems and mitochondrial …

Induced cognitive impairments reversed by grafts of neural precursors: a longitudinal study in a macaque model of parkinson's disease

F Wianny, K Dzahini, K Fifel, CRE Wilson… - Advanced …, 2022 - Wiley Online Library
Parkinson's disease (PD) evolves over an extended and variable period in humans; years
prior to the onset of classical motor symptoms, sleep and biological rhythm disorders …

[PDF][PDF] 11C-and 18F-radiotracers for in vivo imaging of the dopamine system: past, present and future. Biomedicines. 2021; 9: 108

MR Kilbourn - 2021 - pdfs.semanticscholar.org
The applications of positron emission tomography (PET) imaging to study brain
biochemistry, and in particular the aspects of dopamine neurotransmission, have grown …

Positron Emission Tomography of the Reward System

D Romero-Miguel, N Lamanna-Rama… - The Brain Reward …, 2021 - Springer
Recently, great efforts have been focused on understanding and treating reward-related
dysfunction in psychiatric disorders. This has led to preclinical and clinical advances in …