Defining physiological normoxia for improved translation of cell physiology to animal models and humans
TP Keeley, GE Mann - Physiological reviews, 2019 - journals.physiology.org
The extensive oxygen gradient between the air we breathe (Po2~ 21 kPa) and its ultimate
distribution within mitochondria (as low as~ 0.5–1 kPa) is testament to the efforts expended …
distribution within mitochondria (as low as~ 0.5–1 kPa) is testament to the efforts expended …
Coronary atherosclerotic vulnerable plaque: current perspectives
C Stefanadis, CK Antoniou, D Tsiachris… - Journal of the American …, 2017 - Am Heart Assoc
Atherosclerosis is the most common form of vascular disease and constitutes the major
cause of death, with 17.5 million related deaths annually (31% of global mortality). 1 …
cause of death, with 17.5 million related deaths annually (31% of global mortality). 1 …
[PDF][PDF] Nanotechnology for cardiovascular diseases
Q Hu, Z Fang, J Ge, H Li - The Innovation, 2022 - cell.com
Cardiovascular diseases have become the major killers in today's world, among which
coronary artery diseases (CADs) make the greatest contributions to morbidity and mortality …
coronary artery diseases (CADs) make the greatest contributions to morbidity and mortality …
Design of a multivalent bifunctional chelator for diagnostic 64Cu PET imaging in Alzheimer's disease
Herein, we report a 64Cu positron emission tomography (PET) imaging agent that shows
appreciable in vivo brain uptake and exhibits high specific affinity for beta-amyloid (Aβ) …
appreciable in vivo brain uptake and exhibits high specific affinity for beta-amyloid (Aβ) …
Unraveling vascular inflammation: from immunology to imaging
Inflammation is a critical factor in early atherosclerosis and its progression to myocardial
infarction. The search for valid surrogate markers of arterial vascular inflammation led to the …
infarction. The search for valid surrogate markers of arterial vascular inflammation led to the …
[HTML][HTML] Novel positron emission tomography tracers for imaging vascular inflammation
Abstract Purpose of Review To provide a focused update on recent advances in positron
emission tomography (PET) imaging in vascular inflammatory diseases and consider future …
emission tomography (PET) imaging in vascular inflammatory diseases and consider future …
Neutral Ligands as Potential 64Cu Chelators for Positron Emission Tomography Imaging Applications in Alzheimer's Disease
Positron emission tomography (PET), which uses positron-emitting radionuclides to
visualize and measure processes in the human body, is a useful noninvasive diagnostic tool …
visualize and measure processes in the human body, is a useful noninvasive diagnostic tool …
[HTML][HTML] Molecular imaging of aortic aneurysm and its translational power for clinical risk assessment
V Rastogi, SJM Stefens, J Houwaart… - Frontiers in …, 2022 - frontiersin.org
Aortic aneurysms (AAs) are dilations of the aorta, that are often fatal upon rupture.
Diagnostic radiological techniques such as ultrasound (US), magnetic resonance imaging …
Diagnostic radiological techniques such as ultrasound (US), magnetic resonance imaging …
[HTML][HTML] Longitudinal imaging of the ageing mouse
E Dall'Ara, M Boudiffa, C Taylor, D Schug… - Mechanisms of ageing …, 2016 - Elsevier
Several non-invasive imaging techniques are used to investigate the effect of pathologies
and treatments over time in mouse models. Each preclinical in vivo technique provides …
and treatments over time in mouse models. Each preclinical in vivo technique provides …
Synergism of 64Cu-Labeled RGD with Anti-PD-L1 Immunotherapy for the Long-Acting Antitumor Effect
X Wen, X Zeng, J Liu, Y Zhang, C Shi, X Wu… - Bioconjugate …, 2022 - ACS Publications
We put forward a novel targeting-triggering-therapy (TTT) scheme that combines 64Cu-
based targeted radionuclide therapy (TRT) with programmed death-ligand 1 (PD-L1)-based …
based targeted radionuclide therapy (TRT) with programmed death-ligand 1 (PD-L1)-based …