Important pharmacokinetic parameters for individualization of 177Lu‐PSMA therapy: A global sensitivity analysis for a physiologically‐based pharmacokinetic model
D Hardiansyah, P Kletting, NJ Begum, M Eiber… - Medical …, 2021 - Wiley Online Library
Purpose The knowledge of the contribution of anatomical and physiological parameters to
interindividual pharmacokinetic differences could potentially be used to improve …
interindividual pharmacokinetic differences could potentially be used to improve …
[HTML][HTML] Internal dosimetry in F-18 FDG PET examinations based on long-time-measured organ activities using total-body PET/CT: does it make any difference from a …
Purpose A 2-m axial field-of-view, total-body PET/CT scanner (uEXPLORER) has been
recently developed to provide total-body coverage and ultra-high sensitivity, which together …
recently developed to provide total-body coverage and ultra-high sensitivity, which together …
Impact of interpatient variability on organ dose estimates according to MIRD schema: uncertainty and variance‐based sensitivity analysis
A Zvereva, F Kamp, H Schlattl, M Zankl… - Medical …, 2018 - Wiley Online Library
Purpose Variance‐based sensitivity analysis (SA) is described and applied to the radiation
dosimetry model proposed by the Committee on Medical Internal Radiation Dose (MIRD) for …
dosimetry model proposed by the Committee on Medical Internal Radiation Dose (MIRD) for …
Development of computational pregnant female and fetus models and assessment of radiation dose from positron-emitting tracers
Purpose Molecular imaging using PET and hybrid (PET/CT and PET/MR) modalities
nowadays plays a pivotal role in the clinical setting for diagnosis and staging, treatment …
nowadays plays a pivotal role in the clinical setting for diagnosis and staging, treatment …
[HTML][HTML] Common strategic research agenda for radiation protection in medicine
European Association of Nuclear Medicine (EANM)… - Insights into …, 2017 - Springer
Reflecting the change in funding strategies for European research projects, and the goal to
jointly improve medical radiation protection through sustainable research efforts, five …
jointly improve medical radiation protection through sustainable research efforts, five …
Finding sensitive parameters in internal dose calculations for radiopharmaceuticals commonly used in clinical nuclear medicine
V Spielmann, WB Li, M Zankl - Radiation and Environmental Biophysics, 2018 - Springer
Internal dosimetry after incorporation of radionuclides requires standardized biokinetic and
dosimetric models. The aim of the present work was to identify the parameters and the …
dosimetric models. The aim of the present work was to identify the parameters and the …
Patient‐specific anatomical models for radioiodine dosimetry in treatment of hyperthyroidism: is it necessary?
S Khalili, H Miri‐Hakimabad… - Medical …, 2020 - Wiley Online Library
Purpose To investigate the necessity of patient‐specific dosimetry calculations using
individualized models for hyperthyroid patients treated with radioactive iodine (RAI). This …
individualized models for hyperthyroid patients treated with radioactive iodine (RAI). This …
Role of imaging in early-phase trials
L Greene, S Srinivas, S Park, N Hatami… - Novel designs of early …, 2018 - Elsevier
Today the quest for new diagnostic and therapeutic agents is a fervent search akin to the
gold miners and prospectors of the gold rush in the mid-1800s. While rejected rocks far …
gold miners and prospectors of the gold rush in the mid-1800s. While rejected rocks far …
SOLLID–a single centre study to develop methods to investigate the effects of low radiation doses within nuclear medicine, to enable multicentre epidemiological …
G Flux, I Murray, D Rushforth, P Gape… - The British Journal of …, 2021 - academic.oup.com
There is continuing debate concerning the risks of secondary malignancies from low levels
of radiation exposure. The current model used for radiation protection is predicated on the …
of radiation exposure. The current model used for radiation protection is predicated on the …
[HTML][HTML] Uncertainty analysis in internal dose calculations for cerium considering the uncertainties of biokinetic parameters and S values
Radioactive cerium and other lanthanides can be transported through the aquatic system
into foodstuffs and then be incorporated by humans. Information on the uncertainty of …
into foodstuffs and then be incorporated by humans. Information on the uncertainty of …