Functional imaging methods for assessment of minimal residual disease in multiple myeloma: current status and novel immunoPET based methods

N Pandit-Taskar - Seminars in hematology, 2018 - Elsevier
Imaging plays a key role in assessment of myeloma. Osteolytic bone lesions are optimally
assessed using structural imaging, however the structural changes lag the functional …

[HTML][HTML] Molecular imaging of bone metastasis

E Khojasteh, F Dehdashti, M Shokeen - Journal of Bone Oncology, 2023 - ncbi.nlm.nih.gov
Recent advances in molecularly targeted modular designs for in vivo imaging applications
has thrusted open possibilities of investigating deep molecular interactions non-invasively …

[HTML][HTML] CD46-Targeted Theranostics for PET and 225Ac-Radiopharmaceutical Therapy of Multiple Myeloma

A Wadhwa, S Wang, B Patiño-Escobar, AP Bidkar… - Clinical Cancer …, 2024 - AACR
Purpose: Multiple myeloma is a plasma cell malignancy with an unmet clinical need for
improved imaging methods and therapeutics. Recently, we identified CD46 as an …

18F-fluorocholine versus 18F-fluorodeoxyglucose for PET/CT imaging in patients with suspected relapsing or progressive multiple myeloma: a pilot study

T Cassou-Mounat, S Balogova, V Nataf… - European journal of …, 2016 - Springer
Purpose Hybrid positron emission tomography/computed tomography (PET/CT) has now
become available, as well as whole-body, low-dose multidetector row computed …

Preclinical development of CD38-targeted [89Zr] Zr-DFO-daratumumab for imaging multiple myeloma

A Ghai, D Maji, N Cho… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Multiple myeloma (MM) is a plasma B-cell hematologic cancer that causes significant
skeletal morbidity. Despite improvements in survival, heterogeneity in response remains a …

[HTML][HTML] The prognostic significance of [18F]FDG PET/CT in multiple myeloma according to novel interpretation criteria (IMPeTUs)

C Sachpekidis, M Merz, MS Raab, U Bertsch, V Weru… - EJNMMI research, 2021 - Springer
Abstract Purpose [18 F] FDG PET/CT is the elective imaging modality for treatment
monitoring in multiple myeloma (MM). However, MM is a heterogeneous disease from an …

[HTML][HTML] Comparison of Immuno-PET of CD138 and PET imaging with 64CuCl2 and 18F-FDG in a preclinical syngeneic model of multiple myeloma

C Bailly, S Gouard, M Lacombe, P Remaud-Le Saëc… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Purpose Although recent data from the literature suggest that PET imaging with [18]-
Fluorodeoxyglucose (18 F-FDG) is a promising technique in multiple myeloma (MM), the …

Treatment response evaluation with 18F-FDG PET/CT and 18F-NaF PET/CT in multiple myeloma patients undergoing high-dose chemotherapy and autologous stem …

C Sachpekidis, J Hillengass, H Goldschmidt… - European journal of …, 2017 - Springer
Aim The aim of this study was to assess the combined use of the radiotracers 18 F-FDG and
18 F-NaF in treatment response evaluation of a group of multiple myeloma (MM) patients …

Development of [89Zr]DFO-elotuzumab for immunoPET imaging of CS1 in multiple myeloma

A Ghai, A Zheleznyak, M Mixdorf, J O'Neal… - European journal of …, 2021 - Springer
Purpose Multiple myeloma (MM) is a bone marrow malignancy that remains mostly
incurable. Elotuzumab is an FDA-approved therapeutic monoclonal antibody targeted to the …

[HTML][HTML] Assessment of glucose metabolism and cellular proliferation in multiple myeloma: a first report on combined 18F-FDG and 18F-FLT PET/CT imaging

C Sachpekidis, H Goldschmidt, K Kopka… - EJNMMI research, 2018 - Springer
Background Despite the significant upgrading in recent years of the role of 18 F-FDG
PET/CT in multiple myeloma (MM) diagnostics, there is a still unmet need for myeloma …