Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Ongoing research into the application of nanotechnology for cancer treatment and diagnosis
has demonstrated its advantages within contemporary oncology as well as its intrinsic …

Caspases are a family of proteases that play critical roles in controlling inflammation and cell
death. Apoptosis is a caspase-3 mainly controlled behavior to avoid inflammation and …

Enzymatic reactions and self-assembly are two fundamental attributes of cells. It is not
surprising that one can use enzyme-instructed self-assembly (EISA)—the integration of …

Stimuli-responsive in situ self-assembly of small molecule probes into nanostructures has
been promising for the construction of molecular probes for in vivo imaging. In the past few …

Caspase-3 plays irreplaceable roles in apoptosis and related diseases. An imbalance in the
measured levels of Caspase-3 is implicated in irreversible apoptosis. Therefore, the …

The condensation reaction between 6‐hydroxy‐2‐cyanobenzothiazole (CBT) and cysteine
has been shown for various applications such as site‐specific protein labelling and in vivo …

“Smart” biomaterials that are responsive to physiological or biochemical stimuli have found
many biomedical applications for tissue engineering, therapeutics, and molecular imaging …

The molecular imaging of apoptosis remains an important method for the diagnosis and
monitoring of the progression of certain diseases and the evaluation of the efficacy of …