Combination strategies to improve targeted radionuclide therapy
In recent years, targeted radionuclide therapy (TRT) has emerged as a promising strategy
for cancer treatment. In contrast to conventional radiotherapy, TRT delivers ionizing radiation …
for cancer treatment. In contrast to conventional radiotherapy, TRT delivers ionizing radiation …
[HTML][HTML] Perspectives on immunotherapy of metastatic colorectal cancer
Y Dai, W Zhao, L Yue, X Dai, D Rong, F Wu, J Gu… - Frontiers in …, 2021 - frontiersin.org
Colorectal cancer, especially liver metastasis, is still a challenge worldwide. Traditional
treatment such as surgery, chemotherapy and radiotherapy have been difficult to be further …
treatment such as surgery, chemotherapy and radiotherapy have been difficult to be further …
[HTML][HTML] Hypofractionated irradiation has immune stimulatory potential and induces a timely restricted infiltration of immune cells in colon cancer tumors
In addition to locally controlling the tumor, hypofractionated radiotherapy (RT) particularly
aims to activate immune cells in the RT-modified microenvironment. Therefore, we …
aims to activate immune cells in the RT-modified microenvironment. Therefore, we …
Combination radionuclide therapy: a new paradigm
SK Suman, S Subramanian, A Mukherjee - Nuclear Medicine and Biology, 2021 - Elsevier
Targeted molecular radionuclide therapy (MRT) has shown its potential for the treatment of
cancers of multiple origins. A combination therapy strategy employing two or more distinct …
cancers of multiple origins. A combination therapy strategy employing two or more distinct …
Cetuximab enhances radiosensitivity of esophageal squamous cell carcinoma cells by G2/M cycle arrest and DNA repair delay through inhibiting p‐EGFR and p‐ERK
G Zhao, L Feng, T Ye, Y Liu, L Fan, C Ye… - Thoracic …, 2023 - Wiley Online Library
Background Although radiotherapy has improved local control in esophageal squamous cell
carcinoma (ESCC), a considerable number of patients still experience relapse due to …
carcinoma (ESCC), a considerable number of patients still experience relapse due to …
[HTML][HTML] Apigenin enhances the antitumor effects of cetuximab in nasopharyngeal carcinoma by inhibiting EGFR signaling
WJ Hu, J Liu, LK Zhong, J Wang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Nasopharyngeal carcinoma (NPC) is a type of head and neck cancers with poor prognosis.
Despite that platinum-based chemotherapy concurrent with radiotherapy have made great …
Despite that platinum-based chemotherapy concurrent with radiotherapy have made great …
[HTML][HTML] Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer
A Maisonial-Besset, T Witkowski, I Navarro-Teulon… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Tetraspanin 8 (TSPAN8) overexpression is correlated with poor prognosis in
human colorectal cancer (CRC). A murine mAb Ts29. 2 specific for human TSPAN8 …
human colorectal cancer (CRC). A murine mAb Ts29. 2 specific for human TSPAN8 …
Targeted delivery of endosomal escape peptides to enhance immunotoxin potency and anti-cancer efficacy
JR Polli, P Chen, BM Bordeau, JP Balthasar - The AAPS journal, 2022 - Springer
This work describes use of anti-carcinoembryonic antigen antibodies (10H6, T84. 66) for
targeted delivery of an endosomal escape peptide (H6CM18) and gelonin, a type I ribosome …
targeted delivery of an endosomal escape peptide (H6CM18) and gelonin, a type I ribosome …
[HTML][HTML] Therapeutic Characterization of 131I-Labeled Humanized Anti-B7-H3 Antibodies for Radioimmunotherapy for Glioblastoma
F Fu, M Zheng, S Zhao, Y Wang, M Huang, H Chen… - Engineering, 2023 - Elsevier
Abstract B7 homolog 3 (B7-H3) has attracted much attention in glioblastoma (GBM)
radioimmunotherapy (RIT) due to its abnormally high expression on tumor cells. In this …
radioimmunotherapy (RIT) due to its abnormally high expression on tumor cells. In this …
[HTML][HTML] Effective Detection and Monitoring of Glioma Using [18F]FPIA PET Imaging
Background: Reprogrammed cellular metabolism is a cancer hallmark. In addition to
increased glycolysis, the oxidation of acetate in the citric acid cycle is another common …
increased glycolysis, the oxidation of acetate in the citric acid cycle is another common …