A review of nanoparticle drug delivery systems responsive to endogenous breast cancer microenvironment

T Zou, W Lu, Y Mezhuev, M Lan, L Li, F Liu… - European Journal of …, 2021 - Elsevier
Breast cancer, as a malignant disease that seriously threatens women's health, urgently
needs to be researched to develop effective and safe therapeutic drugs. Nanoparticle drug …

[HTML][HTML] A systematic review of molecular imaging agents targeting bradykinin B1 and B2 receptors

J Lau, J Rousseau, D Kwon, F Bénard, KS Lin - Pharmaceuticals, 2020 - mdpi.com
Kinins, bradykinin and kallidin are vasoactive peptides that signal through the bradykinin B1
and B2 receptors (B1R and B2R). B2R is constitutively expressed in healthy tissues and …

177Lu-labeled albumin-binder–conjugated PSMA-targeting agents with extremely high tumor uptake and enhanced tumor-to-kidney absorbed dose ratio

HT Kuo, KS Lin, Z Zhang, CF Uribe… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The use of an albumin binder has been shown to improve tumor uptake of prostate-specific
membrane antigen (PSMA)–targeting radiotherapeutic agents. The aim of this study was to …

Activating TiO2 Nanoparticles: Gallium-68 Serves as a High-Yield Photon Emitter for Cerenkov-Induced Photodynamic Therapy

D Duan, H Liu, Y Xu, Y Han, M Xu… - ACS applied materials …, 2018 - ACS Publications
The classical photodynamic therapy (PDT) requires external light to activate
photosensitizers for cancer treatment. However, limited tissue penetration of light has been a …

Effects of Linker Modification on Tumor-to-Kidney Contrast of 68Ga-Labeled PSMA-Targeted Imaging Probes

HT Kuo, J Pan, Z Zhang, J Lau, H Merkens… - Molecular …, 2018 - ACS Publications
68Ga-PSMA-11 is currently the most popular prostate-specific membrane antigen (PSMA)
radioligand used in the clinic to detect prostate cancer and metastases. However, the high …

[HTML][HTML] Preclinical melanoma imaging with 68Ga-labeled α-melanocyte-stimulating hormone derivatives using PET

C Zhang, Z Zhang, KS Lin, J Pan, I Dude… - Theranostics, 2017 - ncbi.nlm.nih.gov
It is estimated that melanoma accounted for 76,380 new cases and 10,130 deaths in the
United States in 2016. The melanocortin 1 receptor (MC1R) is highly expressed in the vast …

[HTML][HTML] 68Ga-Labeled [Leu13ψThz14]Bombesin(7–14) Derivatives: Promising GRPR-Targeting PET Tracers with Low Pancreas Uptake

L Wang, Z Zhang, H Merkens, J Zeisler, C Zhang… - Molecules, 2022 - mdpi.com
The gastrin-releasing peptide receptor (GRPR) is a G-protein-coupled receptor that is
overexpressed in many solid cancers and is a promising target for cancer imaging and …

ATP/pH Dual Responsive Nanoparticle with d‐[des‐Arg10]Kallidin Mediated Efficient In Vivo Targeting Drug Delivery

Y Zhang, Y Lu, F Wang, S An, Y Zhang, T Sun, J Zhu… - Small, 2017 - Wiley Online Library
Inflammation has been reported as one significant hallmark of breast cancer in relation to
tumor development, metastasis, and invasion. The bradykinin receptor 1 (B1R) is highly …

[HTML][HTML] 68Ga-Labeled [Thz14]Bombesin(7–14) Analogs: Promising GRPR-Targeting Agonist PET Tracers with Low Pancreas Uptake

L Wang, IJ Bratanovic, Z Zhang, HT Kuo, H Merkens… - Molecules, 2023 - mdpi.com
With overexpression in various cancers, the gastrin-releasing peptide receptor (GRPR) is a
promising target for cancer imaging and therapy. However, the high pancreas uptake of …

Radiolabeled B9958 derivatives for imaging bradykinin B1 receptor expression with positron emission tomography: effect of the radiolabel–chelator complex on …

Z Zhang, G Amouroux, J Pan, S Jenni… - Molecular …, 2016 - ACS Publications
Bradykinin B1 receptor (B1R), which is upregulated in a variety of malignancies, is an
attractive cancer imaging biomarker. In this study we optimized the selection of radiolabel …