[HTML][HTML] PET neuroimaging of Alzheimer's disease: radiotracers and their utility in clinical research
W Bao, F Xie, C Zuo, Y Guan… - Frontiers in aging …, 2021 - frontiersin.org
Alzheimer's Disease (AD), the leading cause of senile dementia, is a progressive
neurodegenerative disorder affecting millions of people worldwide and exerting tremendous …
neurodegenerative disorder affecting millions of people worldwide and exerting tremendous …
Imaging of synaptic density in neurodegenerative disorders
PET technology has produced many radiopharmaceuticals that target specific brain proteins
and other measures of brain function. Recently, a new approach has emerged to image …
and other measures of brain function. Recently, a new approach has emerged to image …
Assessing synaptic density in Alzheimer disease with synaptic vesicle glycoprotein 2A positron emission tomographic imaging
Importance Synaptic loss is well established as the major structural correlate of cognitive
impairment in Alzheimer disease (AD). The ability to measure synaptic density in vivo could …
impairment in Alzheimer disease (AD). The ability to measure synaptic density in vivo could …
[HTML][HTML] Can ketones help rescue brain fuel supply in later life? Implications for cognitive health during aging and the treatment of Alzheimer's disease
SC Cunnane, A Courchesne-Loyer… - Frontiers in molecular …, 2016 - frontiersin.org
We propose that brain energy deficit is an important pre-symptomatic feature of Alzheimer's
disease (AD) that requires closer attention in the development of AD therapeutics. Our …
disease (AD) that requires closer attention in the development of AD therapeutics. Our …
Comparison of [11C]UCB-J and [18F]FDG PET in Alzheimer's disease: A tracer kinetic modeling study
[11C] UCB-J PET for synaptic vesicle glycoprotein 2 A (SV2A) has been proposed as a
suitable marker for synaptic density in Alzheimer's disease (AD). We compared [11C] UCB-J …
suitable marker for synaptic density in Alzheimer's disease (AD). We compared [11C] UCB-J …
[HTML][HTML] A high-glycemic diet is associated with cerebral amyloid burden in cognitively normal older adults
MK Taylor, DK Sullivan, RH Swerdlow… - The American journal of …, 2017 - Elsevier
Background Little is known about the relation between dietary intake and cerebral amyloid
accumulation in aging. Objective We assessed the association of dietary glycemic measures …
accumulation in aging. Objective We assessed the association of dietary glycemic measures …
Modifications in resting state functional anticorrelation between default mode network and dorsal attention network: comparison among young adults, healthy elders …
R Esposito, F Cieri, P Chiacchiaretta, N Cera… - Brain imaging and …, 2018 - Springer
Resting state brain activity incorporates different components, including the Default Mode
Network and the Dorsal Attention Network, also known as task-negative network and task …
Network and the Dorsal Attention Network, also known as task-negative network and task …
Neuroimaging of Alzheimer's disease: focus on amyloid and tau PET
H Matsuda, Y Shigemoto, N Sato - Japanese journal of radiology, 2019 - Springer
Although the diagnosis of dementia is still largely a clinical one, based on history and
disease course, neuroimaging has dramatically increased our ability to accurately diagnose …
disease course, neuroimaging has dramatically increased our ability to accurately diagnose …
Clinical validity of brain fluorodeoxyglucose positron emission tomography as a biomarker for Alzheimer's disease in the context of a structured 5-phase development …
The use of Alzheimer's disease (AD) biomarkers is supported in diagnostic criteria, but their
maturity for clinical routine is still debated. Here, we evaluate brain fluorodeoxyglucose …
maturity for clinical routine is still debated. Here, we evaluate brain fluorodeoxyglucose …
Generation of synthetic PET images of synaptic density and amyloid from 18F‐FDG images using deep learning
Purpose Positron emission tomography (PET) imaging with various tracers is increasingly
used in Alzheimer's disease (AD) studies. However, access to PET scans using new or less …
used in Alzheimer's disease (AD) studies. However, access to PET scans using new or less …