[HTML][HTML] EANM procedure guideline for the treatment of liver cancer and liver metastases with intra-arterial radioactive compounds

M Weber, M Lam, C Chiesa, M Konijnenberg… - European journal of …, 2022 - Springer
Primary liver tumours (ie hepatocellular carcinoma (HCC) or intrahepatic
cholangiocarcinoma (ICC)) are among the most frequent cancers worldwide. However, only …

[HTML][HTML] The physics of radioembolization

R Bastiaannet, SC Kappadath, B Kunnen, AJAT Braat… - EJNMMI physics, 2018 - Springer
Radioembolization is an established treatment for chemoresistant and unresectable liver
cancers. Currently, treatment planning is often based on semi-empirical methods, which …

[HTML][HTML] International recommendations for personalised selective internal radiation therapy of primary and metastatic liver diseases with yttrium-90 resin …

H Levillain, O Bagni, CM Deroose, A Dieudonné… - European journal of …, 2021 - Springer
Purpose A multidisciplinary expert panel convened to formulate state-of-the-art
recommendations for optimisation of selective internal radiation therapy (SIRT) with yttrium …

[HTML][HTML] Personalised dosimetry in radioembolisation for HCC: impact on clinical outcome and on trial design

E Garin, X Palard, Y Rolland - Cancers, 2020 - mdpi.com
Selective internal radiation therapy (SIRT) of hepatocellular carcinoma (HCC) has been
used for many years, usually without any specific dosimetry endpoint. Despite good clinical …

[HTML][HTML] The superior predictive value of 166Ho-scout compared with 99mTc-macroaggregated albumin prior to 166Ho-microspheres radioembolization in patients …

MLJ Smits, MG Dassen, JF Prince, AJAT Braat… - European journal of …, 2020 - Springer
Purpose As an alternative to technetium-99m-macroaggregated albumin (99m Tc-MAA), a
scout dose of holmium-166 (166 Ho) microspheres can be used prior to 166 Ho …

Hepatocellular carcinoma tumor dose response after 90Y-radioembolization with glass microspheres using 90Y-SPECT/CT-based voxel dosimetry

SC Kappadath, J Mikell, A Balagopal… - International Journal of …, 2018 - Elsevier
Purpose To investigate hepatocellular carcinoma tumor dose-response characteristics
based on voxel-level absorbed doses (D) and biological effective doses (BED) using …

Targeted radionuclide therapy: an evolution toward precision cancer treatment

H Jadvar - American Journal of Roentgenology, 2017 - Am Roentgen Ray Soc
OBJECTIVE. This article reviews recent developments in targeted radionuclide therapy
(TRT) approaches directed to malignant liver lesions, bone metastases, neuroendocrine …

Correlation of technetium-99m macroaggregated albumin and yttrium-90 glass microsphere biodistribution in hepatocellular carcinoma: a retrospective review of …

P Haste, M Tann, S Persohn, T LaRoche… - Journal of Vascular and …, 2017 - Elsevier
Purpose To evaluate whether technetium-99 (99m Tc)-labeled macroaggregated albumin
(MAA) can predict subsequent yttrium-90 (90 Y) distribution and imaging response in …

Trans-arterial radioembolization dosimetry in 2022

E Garin, B Guiu, J Edeline, Y Rolland… - CardioVascular and …, 2022 - Springer
Trans-arterial radioembolization is currently performed using 90Y-loaded glass or resin
microspheres and also using 166Ho-loaded microspheres. The goal of this review is to …

High impact of macroaggregated albumin‐based tumour dose on response and overall survival in hepatocellular carcinoma patients treated with 90Y‐loaded glass …

E Garin, Y Rolland, M Pracht, S Le Sourd… - Liver …, 2017 - Wiley Online Library
Abstract Background & Aims Efficacy of radioembolization is derived from radioinduced
damage, whereas tumour dosimetry is not considered as yet in prospective clinical trials …