Radiotheranostics in cancer diagnosis and management

H Jadvar, X Chen, W Cai, U Mahmood - Radiology, 2018 - pubs.rsna.org
The fundamental foundation for precision medicine is accurate and specific targeting of
cancer cells. Advances in the understanding of cancer biology, developments in diagnostic …

[HTML][HTML] Neurotheranostics as personalized medicines

BD Kevadiya, BM Ottemann, MB Thomas… - Advanced Drug Delivery …, 2019 - Elsevier
The discipline of neurotheranostics was forged to improve diagnostic and therapeutic
clinical outcomes for neurological disorders. Research was facilitated, in largest measure …

Optimizing iodine capture performance by metal-organic framework containing with bipyridine units

X Yang, X Liu, Y Liu, XF Wang, Z Chen… - Frontiers of Chemical …, 2023 - Springer
Radioactive iodine exhibits medical values in radiology, but its excessive emissions can
cause environmental pollution. Thus, the capture of radioiodine poses significant …

Targeted radionuclide therapy: an evolution toward precision cancer treatment

H Jadvar - American Journal of Roentgenology, 2017 - Am Roentgen Ray Soc
OBJECTIVE. This article reviews recent developments in targeted radionuclide therapy
(TRT) approaches directed to malignant liver lesions, bone metastases, neuroendocrine …

β-radiating radionuclides in cancer treatment, novel insight into promising approach

S Asadian, H Mirzaei, BA Kalantari… - Pharmacological …, 2020 - Elsevier
Targeted radionuclide therapy, known as molecular radiotherapy is a novel therapeutic
module in cancer medicine. β-radiating radionuclides have definite impact on target cells via …

Defining radioiodine-refractory differentiated thyroid cancer: efficacy and safety of lenvatinib by radioiodine-refractory criteria in the SELECT trial

N Kiyota, B Robinson, M Shah, AO Hoff, MH Taylor… - Thyroid, 2017 - liebertpub.com
Background: While there is a clear consensus for defining radioiodine-refractory
differentiated thyroid cancer (RR-DTC), it is unknown whether these criteria are equally valid …

Development of companion diagnostics

DA Mankoff, CE Edmonds, MD Farwell… - Seminars in nuclear …, 2016 - Elsevier
The goal of individualized and targeted treatment and precision medicine requires the
assessment of potential therapeutic targets to direct treatment selection. The biomarkers …

Radiopharmaceutical Chemistry and Drug Development—What's Changed?

CA Kunos, DA Mankoff, MK Schultz, SA Graves… - Seminars in radiation …, 2021 - Elsevier
Radiation oncologists and nuclear medicine physicians have seen a resurgence in the
clinical use of radiopharmaceuticals for the curative or palliative treatment of cancer. To …

Building the bridge: molecular imaging biomarkers for 21st century cancer therapies

MA Sellmyer, IK Lee, DA Mankoff - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
Precision medicine, in which the molecular underpinnings of the disease are assessed for
tailored therapies, has greatly impacted cancer care. In parallel, a new pillar of therapeutics …

Perspectives for concepts of individualized radionuclide therapy, molecular radiotherapy, and theranostic approaches

M Hosono - Nuclear medicine and molecular imaging, 2019 - Springer
Radionuclide therapy (RNT) stands on the delivery of radiation to tumors or non-tumor target
organs using radiopharmaceuticals that are designed to have specific affinity to targets. RNT …