Radioactive transition metals for imaging and therapy
E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …
emission tomography (PET) and single-photon imaging, including single-photon emission …
[HTML][HTML] Radiometals in Imaging and Therapy: Highlighting Two Decades of Research
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …
[HTML][HTML] Production of radiometals in liquid targets
Over the last several years, the use of radiometals has gained increasing relevance in
supporting the continuous development of new, complementary and more specific biological …
supporting the continuous development of new, complementary and more specific biological …
[HTML][HTML] Cyclotron production of PET radiometals in liquid targets: aspects and prospects
MK Pandey, TR DeGrado - Current radiopharmaceuticals, 2021 - ncbi.nlm.nih.gov
The present review describes the methodological aspects and prospects of the production of
Positron Emission Tomography (PET) radiometals in a liquid target using low-medium …
Positron Emission Tomography (PET) radiometals in a liquid target using low-medium …
Insights into trace metal metabolism in health and disease from PET:“PET metallomics”
JJ Bartnicka, PJ Blower - Journal of Nuclear Medicine, 2018 - Soc Nuclear Med
Essential trace metals such as copper, zinc, iron, and manganese perform critical functions
in cellular and physiologic processes including catalytic, regulatory, and signaling roles …
in cellular and physiologic processes including catalytic, regulatory, and signaling roles …
Production of Y-86 and other radiometals for research purposes using a solution target system
Introduction Diagnostic radiometals are typically obtained from cyclotrons by irradiating solid
targets or from radioisotope generators. These methods have the advantage of high …
targets or from radioisotope generators. These methods have the advantage of high …
[HTML][HTML] Recovery of Gallium-68 and Zinc from HNO3-Based Solution by Liquid–Liquid Extraction with Arylamino Phosphonates
F Zhuravlev, A Gulzar, L Falborg - Molecules, 2022 - mdpi.com
The cyclotron production of gallium-68 via the 68Zn (p, n) 68Ga nuclear reaction in liquid
targets is gaining significant traction in clinics. This work describes (1) the synthesis of new …
targets is gaining significant traction in clinics. This work describes (1) the synthesis of new …
Expanding PET-applications in life sciences with positron-emitters beyond fluorine-18
HH Coenen, J Ermert - Nuclear medicine and biology, 2021 - Elsevier
Abstract Positron-emission-tomography (PET) has become an indispensable diagnostic tool
in modern nuclear medicine. Its outstanding molecular imaging features allow repetitive …
in modern nuclear medicine. Its outstanding molecular imaging features allow repetitive …
[HTML][HTML] Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission …
G Firth, E Georgiadou, A Griffiths, M Amrahli… - Frontiers in …, 2023 - frontiersin.org
Introduction Common variants in the SLC30A8 gene, encoding the secretory granule zinc
transporter ZnT8 (expressed largely in pancreatic islet alpha and beta cells), are associated …
transporter ZnT8 (expressed largely in pancreatic islet alpha and beta cells), are associated …
Imaging zinc trafficking in vivo by positron emission tomography with zinc-62
G Firth, Z Yu, JJ Bartnicka, D Parker, J Kim… - Metallomics, 2022 - academic.oup.com
Non-invasive imaging techniques to dynamically map whole-body trafficking of essential
metals in vivo in health and diseases are needed. Despite 62Zn having appropriate physical …
metals in vivo in health and diseases are needed. Despite 62Zn having appropriate physical …