Imaging the substantia nigra in Parkinson disease and other Parkinsonian syndromes
Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
The Parkinson's progression markers initiative (PPMI)–establishing a PD biomarker cohort
K Marek, S Chowdhury, A Siderowf… - Annals of clinical …, 2018 - Wiley Online Library
Abstract Objective The Parkinson's Progression Markers Initiative (PPMI) is an
observational, international study designed to establish biomarker‐defined cohorts and …
observational, international study designed to establish biomarker‐defined cohorts and …
The future of nuclear medicine as an independent specialty
J Czernin, I Sonni, A Razmaria… - Journal of Nuclear …, 2019 - Soc Nuclear Med
In this article, we provide an overview of established and emerging conventional nuclear
medicine and PET imaging biomarkers, as the diagnostic nuclear medicine portfolio is …
medicine and PET imaging biomarkers, as the diagnostic nuclear medicine portfolio is …
Diagnostic accuracy of dopaminergic imaging in prodromal dementia with Lewy bodies
BackgroundDopaminergic imaging has high diagnostic accuracy for dementia with Lewy
bodies (DLB) at the dementia stage. We report the first investigation of dopaminergic …
bodies (DLB) at the dementia stage. We report the first investigation of dopaminergic …
Automatic classification of dopamine transporter SPECT: deep convolutional neural networks can be trained to be robust with respect to variable image characteristics
Purpose This study investigated the potential of deep convolutional neural networks (CNN)
for automatic classification of FP-CIT SPECT in multi-site or multi-camera settings with …
for automatic classification of FP-CIT SPECT in multi-site or multi-camera settings with …
[HTML][HTML] Nuclear imaging in the diagnosis of clinically uncertain parkinsonian syndromes
R Buchert, C Buhmann, I Apostolova… - Deutsches Ärzteblatt …, 2019 - ncbi.nlm.nih.gov
Background Parkinsonian syndromes are classified by etiology mainly on clinical grounds,
that is, on the basis of the clinical manifestations and with the aid of conventional ancillary …
that is, on the basis of the clinical manifestations and with the aid of conventional ancillary …
Diagnostic performance of the visual reading of 123I-Ioflupane SPECT images with or without quantification in patients with movement disorders or dementia
Visual interpretation of 123I-ioflupane SPECT images has high diagnostic accuracy for
differentiating parkinsonian syndromes (PS), from essential tremor and probable dementia …
differentiating parkinsonian syndromes (PS), from essential tremor and probable dementia …
[HTML][HTML] No impact of attenuation and scatter correction on the interpretation of dopamine transporter SPECT in patients with clinically uncertain parkinsonian …
T Schiebler, I Apostolova, FL Mathies, C Lange… - European Journal of …, 2023 - Springer
Purpose The benefit from attenuation and scatter correction (ASC) of dopamine transporter
(DAT)-SPECT for the detection of nigrostriatal degeneration in clinical routine is still a matter …
(DAT)-SPECT for the detection of nigrostriatal degeneration in clinical routine is still a matter …
[HTML][HTML] Deep learning regressor model based on nigrosome MRI in Parkinson syndrome effectively predicts striatal dopamine transporter-SPECT uptake
Purpose Nigrosome imaging using susceptibility-weighted imaging (SWI) and dopamine
transporter imaging using 123I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) …
transporter imaging using 123I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) …
Improving the diagnosis and management of Lewy body dementia: the DIAMOND-Lewy research programme including pilot cluster RCT
Background: Lewy body dementia, comprising both dementia with Lewy bodies and
Parkinson's disease dementia, is the second commonest cause of neurodegenerative …
Parkinson's disease dementia, is the second commonest cause of neurodegenerative …