Inhibiting metastasis and preventing tumor relapse by triggering host immunity with tumor-targeted photodynamic therapy using photosensitizer-loaded functional …
Effective cancer therapy depends not only on destroying the primary tumor but also on
conditioning the host immune system to recognize and eliminate residual tumor cells and …
conditioning the host immune system to recognize and eliminate residual tumor cells and …
Enhancing anti-PD-1/PD-L1 immune checkpoint inhibitory cancer therapy by CD276-targeted photodynamic ablation of tumor cells and tumor vasculature
Antiangiogenic therapies have been demonstrated to improve the efficacy of immune
checkpoint inhibition by overcoming the immunosuppressive status of the tumor …
checkpoint inhibition by overcoming the immunosuppressive status of the tumor …
[HTML][HTML] Enhanced anti-tumor efficacy through a combination of integrin αvβ6-targeted photodynamic therapy and immune checkpoint inhibition
Abstract “Training” the host immune system to recognize and systemically eliminate residual
tumor lesions and micrometastases is a promising strategy for cancer therapy. In this study …
tumor lesions and micrometastases is a promising strategy for cancer therapy. In this study …
[HTML][HTML] Noninvasive imaging of CD206-positive M2 macrophages as an early biomarker for post-chemotherapy tumor relapse and lymph node metastasis
Tumor relapse after initial regression post-chemotherapy is a major challenge in cancer
treatment, as it usually leads to local-regional recurrence or inoperable distant metastasis …
treatment, as it usually leads to local-regional recurrence or inoperable distant metastasis …
Inhibition of tumor growth and metastasis by photoimmunotherapy targeting tumor-associated macrophage in a sorafenib-resistant tumor model
Tumor-associated macrophages (TAMs) play essential roles in tumor invasion and
metastasis, and contribute to drug resistance. Clinical evidence suggests that TAM levels …
metastasis, and contribute to drug resistance. Clinical evidence suggests that TAM levels …
Albumin-Mediated Biomineralization of Paramagnetic NIR Ag2S QDs for Tiny Tumor Bimodal Targeted Imaging in Vivo
J Zhang, G Hao, C Yao, J Yu, J Wang… - … applied materials & …, 2016 - ACS Publications
Bimodal imaging has captured increasing interests due to its complementary characteristics
of two kinds of imaging modalities. Among the various dual-modal imaging techniques …
of two kinds of imaging modalities. Among the various dual-modal imaging techniques …
[HTML][HTML] Molecular imaging of tumor-infiltrating macrophages in a preclinical mouse model of breast cancer
Significant evidence has indicated that tumor-associated macrophages (TAMs) play a critical
role in the proliferation, invasion, angiogenesis, and metastasis of a variety of human …
role in the proliferation, invasion, angiogenesis, and metastasis of a variety of human …
[HTML][HTML] The Emerging Use of In Vivo Optical Imaging in the Study of Neurodegenerative Diseases
The detection and subsequent quantification of photons emitted from living tissues, using
highly sensitive charged-couple device (CCD) cameras, have enabled investigators to …
highly sensitive charged-couple device (CCD) cameras, have enabled investigators to …
A near-infrared phthalocyanine dye-labeled agent for integrin αvβ6-targeted theranostics of pancreatic cancer
Integrin αvβ6 is widely upregulated in variant malignant cancers but is undetectable in
normal organs, making it a promising target for cancer diagnostic imaging and therapy …
normal organs, making it a promising target for cancer diagnostic imaging and therapy …
C/EBPβ promotes angiogenesis through secretion of IL‐6, which is inhibited by genistein, in EGFRvIII‐positive glioblastoma
X Liu, K Liu, J Qin, L Hao, X Li, Y Liu… - … journal of cancer, 2015 - Wiley Online Library
To study the mechanisms underlying the IL‐6‐promoted angiogenic microenvironment in
EGFRvIII‐positive glioblastoma, VEGF expression in EGFRvIII‐positive/negative tumors was …
EGFRvIII‐positive glioblastoma, VEGF expression in EGFRvIII‐positive/negative tumors was …