[HTML][HTML] Somatostatin analogues in the treatment of neuroendocrine tumors: past, present and future

AK Stueven, A Kayser, C Wetz, H Amthauer… - International journal of …, 2019 - mdpi.com
In recent decades, the incidence of neuroendocrine tumors (NETs) has steadily increased.
Due to the slow-growing nature of these tumors and the lack of early symptoms, most cases …

Lutetium-177 therapeutic radiopharmaceuticals: linking chemistry, radiochemistry, and practical applications

S Banerjee, MRA Pillai, FF Knapp - Chemical reviews, 2015 - ACS Publications
Interest in the use of radionuclides for treatment of various diseases has a long history and
parallels the isolation of radium by Marie and Pierre Curie in the early part of the 20th …

The North American Neuroendocrine Tumor Society consensus paper on the surgical management of pancreatic neuroendocrine tumors

JR Howe, NB Merchant, C Conrad, XM Keutgen… - Pancreas, 2020 - journals.lww.com
This manuscript is the result of the North American Neuroendocrine Tumor Society
consensus conference on the surgical management of pancreatic neuroendocrine tumors …

The North American neuroendocrine tumor society consensus guidelines for surveillance and medical management of pancreatic neuroendocrine tumors

TR Halfdanarson, JR Strosberg, L Tang, AM Bellizzi… - Pancreas, 2020 - journals.lww.com
This article is the result of the North American Neuroendocrine Tumor Society consensus
conference on the medical management of pancreatic neuroendocrine tumors from July 19 …

Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic …

A Rinke, M Wittenberg, C Schade-Brittinger… - …, 2016 - karger.com
Background: Somatostatin analogs have been shown to control the growth of well-
differentiated metastatic neuroendocrine tumors. Their effect on overall survival is a matter of …

[HTML][HTML] Prospective observational study of 177Lu-DOTA-octreotate therapy in 200 patients with advanced metastasized neuroendocrine tumours (NETs): feasibility …

U Garske-Román, M Sandström, K Fröss Baron… - European journal of …, 2018 - Springer
Purpose Peptide receptor radionuclide therapy in patients with neuroendocrine tumours has
yielded promising results. This prospective study investigated the feasibility of dosimetry of …

PRRT neuroendocrine tumor response monitored using circulating transcript analysis: the NETest

L Bodei, MS Kidd, A Singh, WA van der Zwan… - European journal of …, 2020 - Springer
Purpose Peptide receptor radionuclide therapy (PRRT) is effective for metastatic/inoperable
neuroendocrine tumors (NETs). Imaging response assessment is usually efficient …

[HTML][HTML] Impact of liver tumour burden, alkaline phosphatase elevation, and target lesion size on treatment outcomes with 177Lu-Dotatate: an analysis of the NETTER …

J Strosberg, PL Kunz, A Hendifar, J Yao… - European journal of …, 2020 - Springer
Purpose To assess the impact of baseline liver tumour burden, alkaline phosphatase (ALP)
elevation, and target lesion size on treatment outcomes with 177 Lu-Dotatate. Methods In …

PRRT genomic signature in blood for prediction of 177Lu-octreotate efficacy

L Bodei, MS Kidd, A Singh, WA Van Der Zwan… - European journal of …, 2018 - Springer
Background Peptide receptor radionuclide therapy (PRRT) utilizes somatostatin receptor
(SSR) overexpression on neuroendocrine tumors (NET) to deliver targeted radiotherapy …

Radionuclide therapy for neuroendocrine tumors

M Cives, J Strosberg - Current oncology reports, 2017 - Springer
Peptide receptor radionuclide therapy (PRRT) is a form of systemic radiotherapy that allows
targeted delivery of radionuclides to tumor cells expressing high levels of somatostatin …