Abstract Astatine-211 (211 At, t 1/2= 7.21 h) emitting two α particles with energies of 5.87
and 7.45 MeV, can lead to a high linear energy transfer (LET= 98.84 keV/µm) and short …

Auger electron (AE) radiopharmaceutical therapy (RPT) may have the same therapeutic
efficacy as α-particles for oncologic small disease, with lower risks of normal-tissue toxicity …

Epithelial ovarian cancer (EOC) is often asymptomatic and presents clinically in an
advanced stage as widespread peritoneal microscopic disease that is generally considered …

Background Absorbed doses for α-emitters are different from those for β-emitters, as the high
linear energy transfer (LET) nature of α-particles results in a very dense energy deposition …

Auger electrons can be highly radiotoxic when they are used to irradiate specific molecular
sites. This has spurred basic science investigations of their radiobiological effects and …

Background Targeted alpha therapy has been postulated to have great potential for the
treatment of small clusters of tumour cells as well as small metastases. 213 Bismuth, an α …

Pancreatic ductal adenocarcinoma (PDAC) has long been associated with low survival
rates. A lack of accurate diagnostic tests and limited treatment options contribute to the poor …

Prostate cancer (PCa) is one of the most common cancers in men and is the second leading
cause of cancer-related deaths in the USA. In the United States, it is the second most …

Accumulating evidence indicates that cancer stem cells (CSCs) are the cause of tumor
drug/radio-resistance or distant metastasis; therefore, it is essential to eliminate CSCs to …

Purpose The aim of this study was to perform radiotheranostics with radioiodinated
monoclonal antibodies (mAbs) for targeting cancer stem cells (CSCs) in human colorectal …