The human epidermal growth factor receptor family (EGFR-family, other designations: HER
family, RTK Class I) is strongly linked to oncogenic transformation. Its members are …

Head and neck squamous cell carcinomas (HNSCCs) are often aggressive, making
advanced disease very difficult to treat using contemporary modalities, such as surgery …

Tumor biomarkers play important roles in tumor growth, invasion, and metastasis. Imaging of
specific biomarkers will help to understand different biological activities, thereby achieving …

Approximately 50,000 new cases of head and neck squamous cell carcinoma (HNSCC) are
diagnosed worldwide each year and subsequently treated with surgery, chemotherapy …

Overexpression of the epidermal growth factor receptor (EGFR) is linked to an adverse
outcome in various solid tumors. Cetuximab is an EGFR inhibitor, which in combination with …

Treatment of head and neck squamous cell carcinomas with radiotherapy and the epidermal
growth factor receptor (EGFR) inhibitor cetuximab shows an improved response in a …

Epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor that activates
downstream signaling pathways, including the Ras-MEK-Erk and PI3K-AKT pathways …

Background To determine whether 18F‐PET/CT is able to identify treatment response as
early as 1 week after the end of chemoradiotherapy, whether 18F‐PET/CT can identify …

Molecular imaging of specific biomarkers can have prognostic, predictive or monitoring
value in head and neck squamous cell carcinoma (HNSCC). The epidermal growth factor …

We aim to characterize the metabolic changes associated with early response to radiation
therapy in a prostate cancer mouse model by 2-deoxy-2-[18F] fluoro-d-glucose ([18F] FDG) …