Cardiomyopathy is a manifestation of transthyretin amyloidosis (ATTR), which is an
underrecognized systemic disease whereby the transthyretin protein misfolds to form fibrils …

Tissue deposition of protein fibrils causes a group of rare diseases called systemic
amyloidoses. This Seminar focuses on changes in their epidemiology, the current approach …

Cardiac amyloidosis is a form of restrictive infiltrative cardiomyopathy that confers significant
mortality. Due to the relative rarity of cardiac amyloidosis, clinical and diagnostic expertise in …

Cardiac amyloidosis (CA) is one of the most rapidly progressive forms of heart disease, with
a median survival from diagnosis, if untreated, ranging from< 6 months for light chain …

The aggregation of specific proteins is hypothesized to underlie several degenerative
diseases, which are collectively known as amyloid disorders. However, the mechanistic …

With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in
cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with …

Systemic amyloidosis encompasses a debilitating, under-diagnosed but increasingly
recognized group of disorders characterized by the extracellular deposition of misfolded …

Cardiac involvement drives prognosis and treatment choices in cardiac amyloidosis.
Echocardiography is the first-line examination for patients presenting with heart failure, and …

Purpose Cardiac amyloidosis, a restrictive heart disease with high mortality and morbidity, is
underdiagnosed due to limited targeted diagnostic imaging. The primary aim of this study …

Amyloid light chain (AL) amyloidosis is a systemic disease characterised by the aggregation
of misfolded immunoglobulin light chain (LC), predominantly in the heart and kidneys …