The chicken chorioallantoic membrane model in biology, medicine and bioengineering
The chicken chorioallantoic membrane (CAM) is a simple, highly vascularized
extraembryonic membrane, which performs multiple functions during embryonic …
extraembryonic membrane, which performs multiple functions during embryonic …
The chick embryo chorioallantoic membrane as a model for tumor biology
D Ribatti - Experimental cell research, 2014 - Elsevier
Among the in vivo models, the chick embryo chorioallantoic membrane (CAM) has been
used to implant several tumor types as well as malignant cell lines to study their growth rate …
used to implant several tumor types as well as malignant cell lines to study their growth rate …
[HTML][HTML] The CAM Model—Q&a with experts
Simple Summary The chorioallantoic membrane (CAM) model is an alternative in vivo test
system for the study of hallmarks of cancer such as angiogenesis, tumor growth, immune …
system for the study of hallmarks of cancer such as angiogenesis, tumor growth, immune …
[HTML][HTML] Utilisation of chick embryo chorioallantoic membrane as a model platform for imaging-navigated biomedical research
L Chen, S Wang, Y Feng, J Zhang, Y Du, J Zhang… - Cells, 2021 - mdpi.com
The fertilised chick egg and particularly its chorioallantoic membrane (CAM) have drawn
continuing interest in biomedicine and bioengineering fields, especially for research on …
continuing interest in biomedicine and bioengineering fields, especially for research on …
Chorioallantoic membrane assay as model for angiogenesis in tissue engineering: Focus on stem cells
G Merckx, H Tay, M Lo Monaco… - … Engineering Part B …, 2020 - liebertpub.com
Tissue engineering aims to structurally and functionally regenerate damaged tissues, which
requires the formation of new blood vessels that supply oxygen and nutrients by the process …
requires the formation of new blood vessels that supply oxygen and nutrients by the process …
[HTML][HTML] Exploitation of the chick embryo chorioallantoic membrane (CAM) as a platform for anti-metastatic drug testing
P Pawlikowska, T Tayoun, M Oulhen, V Faugeroux… - Scientific reports, 2020 - nature.com
The establishment of clinically relevant models for tumor metastasis and drug testing is a
major challenge in cancer research. Here we report a physiologically relevant assay …
major challenge in cancer research. Here we report a physiologically relevant assay …
[HTML][HTML] Optimization of the chicken chorioallantoic membrane assay as reliable in vivo model for the analysis of osteosarcoma
P Kunz, A Schenker, H Sähr, B Lehner, J Fellenberg - PLoS One, 2019 - journals.plos.org
Survival rates of osteosarcoma patients could not be significantly improved by conventional
chemotherapeutic treatment regimens since the introduction of high-dose chemotherapy 35 …
chemotherapeutic treatment regimens since the introduction of high-dose chemotherapy 35 …
Tumor grafted–chick chorioallantoic membrane as an alternative model for biological cancer research and conventional/nanomaterial-based theranostics evaluation
AK Mapanao, PP Che, P Sarogni, P Sminia… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Advancements in cancer management and treatment are associated with
strong preclinical research data, in which reliable cancer models are demanded. Indeed …
strong preclinical research data, in which reliable cancer models are demanded. Indeed …
The CAM assay as an alternative in vivo model for drug testing
R Schneider-Stock, D Ribatti - Organotypic Models in Drug Development, 2021 - Springer
In the last decade, the chicken chorioallantoic membrane (CAM) assay has been re-
discovered in cancer research to study the molecular mechanisms of anti-cancer drug …
discovered in cancer research to study the molecular mechanisms of anti-cancer drug …
Bridging the In Vitro to In Vivo gap: Using the Chick Embryo Model to Accelerate Nanoparticle Validation and Qualification for In Vivo studies
We postulate that nanoparticles (NPs) for use in therapeutic applications have largely not
realized their clinical potential due to an overall inability to use in vitro results to predict NP …
realized their clinical potential due to an overall inability to use in vitro results to predict NP …