The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

[HTML][HTML] Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Clearance pathways and tumor targeting of imaging nanoparticles

M Yu, J Zheng - ACS nano, 2015 - ACS Publications
A basic understanding of how imaging nanoparticles are removed from the normal
organs/tissues but retained in the tumors is important for their future clinical applications in …

Upconverting nanoparticles: assessing the toxicity

A Gnach, T Lipinski, A Bednarkiewicz… - Chemical Society …, 2015 - pubs.rsc.org
Lanthanide doped nanoparticles (Ln: NPs) hold promise as novel luminescent probes for
numerous applications in nanobiophotonics. Despite excellent photostability, narrowband …

Polymeric nanostructures for imaging and therapy

M Elsabahy, GS Heo, SM Lim, G Sun… - Chemical …, 2015 - ACS Publications
Medical diagnosis and therapy are essential for providing patients with proper care,
although inefficient diagnosis and therapy are usually associated with either improper …

Meta-analysis of nanoparticle delivery to tumors using a physiologically based pharmacokinetic modeling and simulation approach

YH Cheng, C He, JE Riviere, NA Monteiro-Riviere… - ACS …, 2020 - ACS Publications
Numerous studies have engineered nanoparticles with different physicochemical properties
to enhance the delivery efficiency to solid tumors, yet the mean and median delivery …

Designing stimuli‐responsive upconversion nanoparticles that exploit the tumor microenvironment

M Ovais, S Mukherjee, A Pramanik, D Das… - Advanced …, 2020 - Wiley Online Library
Tailoring personalized cancer nanomedicines demands detailed understanding of the tumor
microenvironment. In recent years, smart upconversion nanoparticles with the ability to …

New advances in pre-clinical diagnostic imaging perspectives of functionalized upconversion nanoparticle-based nanomedicine

AA Ansari, AK Parchur, ND Thorat, G Chen - Coordination Chemistry …, 2021 - Elsevier
In widespread progress of nanoparticles (NPs) based biomedical applications particularly in
leukemia cancer treatment. Upconversion nanoparticles (UCNPs) demonstrated outstanding …

Magnetic/Upconversion Fluorescent NaGdF4:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo

C Liu, Z Gao, J Zeng, Y Hou, F Fang, Y Li, R Qiao… - ACS …, 2013 - ACS Publications
Detection of early malignant tumors remains clinically difficult; developing ultrasensitive
imaging agents is therefore highly demanded. Owing to the unusual magnetic and optical …

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

J Ge, Q Zhang, J Zeng, Z Gu, M Gao - Biomaterials, 2020 - Elsevier
Nuclear medicine imaging has been developed as a powerful diagnostic approach for
cancers by detecting gamma rays directly or indirectly from radionuclides to construct …