ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Fluorescence-guided surgery with live molecular navigation—a new cutting edge

QT Nguyen, RY Tsien - Nature reviews cancer, 2013 - nature.com
A glowing new era in cancer surgery may be dawning. Using fluorescently labelled markers,
surgical molecular navigation means that tumours and nerves can be displayed in real time …

Safety and tumor specificity of cetuximab-IRDye800 for surgical navigation in head and neck cancer

EL Rosenthal, JM Warram, E De Boer, TK Chung… - Clinical Cancer …, 2015 - AACR
Purpose: Positive margins dominate clinical outcomes after surgical resections in most solid
cancer types, including head and neck squamous cell carcinoma. Unfortunately, surgeons …

[HTML][HTML] Fluid shear stress activates YAP1 to promote cancer cell motility

HJ Lee, MF Diaz, KM Price, JA Ozuna, S Zhang… - Nature …, 2017 - nature.com
Mechanical stress is pervasive in egress routes of malignancy, yet the intrinsic effects of
force on tumour cells remain poorly understood. Here, we demonstrate that frictional force …

In vivo imaging with antibodies and engineered fragments

AC Freise, AM Wu - Molecular immunology, 2015 - Elsevier
Antibodies have clearly demonstrated their utility as therapeutics, providing highly selective
and effective drugs to treat diseases in oncology, hematology, cardiology, immunology and …

PET/fluorescence imaging: An overview of the chemical strategies to build dual imaging tools

J Ariztia, K Solmont, NP Moïse, S Specklin… - Bioconjugate …, 2022 - ACS Publications
Molecular imaging is a biomedical research discipline that has quickly emerged to afford the
observation, characterization, monitoring, and quantification of biomarkers and biological …

A review of performance of near-infrared fluorescence imaging devices used in clinical studies

B Zhu, EM Sevick-Muraca - The British journal of radiology, 2015 - academic.oup.com
Near-infrared fluorescence (NIRF) molecular imaging holds great promise as a new “point-of-
care” medical imaging modality that can potentially provide the sensitivity of nuclear …

Targeted multimodal imaging modalities

SY Lee, SI Jeon, S Jung, IJ Chung, CH Ahn - Advanced drug delivery …, 2014 - Elsevier
Molecular imaging non-invasively visualizes and characterizes the biologic functions and
mechanisms in living organisms at a molecular level. In recent years, advances in imaging …

[HTML][HTML] Emerging lymphatic imaging technologies for mouse and man

EM Sevick-Muraca, S Kwon… - The Journal of clinical …, 2014 - Am Soc Clin Investig
The lymphatic circulatory system has diverse functions in lipid absorption, fluid homeostasis,
and immune surveillance and responds dynamically when presented with infection …

18F-Positron Emitting/Trimethine Cyanine-Fluorescent Contrast for Image-Guided Prostate Cancer Management

H Kommidi, H Guo, F Nurili, Y Vedvyas… - Journal of medicinal …, 2018 - ACS Publications
[18/19F]-4, an anionic GCPII/PSMA inhibitor for image-guided intervention in prostate
cancer, is described.[19F]-4 is radiolabeled with a radiochemical yield that is≥ 27% and a …