Where is dopamine and how do immune cells see it?: dopamine-mediated immune cell function in health and disease
SM Matt, PJ Gaskill - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …
functions in a variety of peripheral systems. Growing research has also shown that …
[HTML][HTML] Molecular targets for PET imaging of activated microglia: the current situation and future expectations
C Tronel, B Largeau, MJ Santiago Ribeiro… - International journal of …, 2017 - mdpi.com
Microglia, as cellular mediators of neuroinflammation, are implicated in the pathogenesis of
a wide range of neurodegenerative diseases. Positron emission tomography (PET) imaging …
a wide range of neurodegenerative diseases. Positron emission tomography (PET) imaging …
Imaging neuroinflammation in Alzheimer's disease and other dementias: recent advances and future directions
Abstract Alzheimer's disease (AD), dementia with Lewy bodies, frontotemporal dementia
(FTD), and Huntington's disease (HD) are the main neurodegenerative causes of dementia …
(FTD), and Huntington's disease (HD) are the main neurodegenerative causes of dementia …
A near-infrared fluorescent probe with large stokes shift for accurate detection of β‑glucuronidase in living cells and mouse models
X Wei, M Hao, XX Hu, Z Song, Y Wang, R Sun… - Sensors and Actuators B …, 2021 - Elsevier
Abstract β-Glucuronidase (GLU) plays a vital role in the growth, migration, angiogenesis,
and metastasis of tumors. The reliable detection of GLU is an effective approach for early …
and metastasis of tumors. The reliable detection of GLU is an effective approach for early …
An enzyme-activated two-photon ratiometric fluorescent probe with lysosome targetability for imaging β-glucuronidase in colon cancer cells and tissue
X Wei, J Li, X Yang, B Dong, B Geng, Z Li, X Hu… - Analytica Chimica …, 2022 - Elsevier
Colon cancer is a malignant neoplasm with high mortality that has seriously threatened
human life. Accumulating evidence reveals that the β-glucuronidase (GLU), a lysosomal …
human life. Accumulating evidence reveals that the β-glucuronidase (GLU), a lysosomal …
[HTML][HTML] Real-time imaging of intestinal bacterial β-glucuronidase activity by hydrolysis of a fluorescent probe
Intestinal bacterial β-glucuronidase (βG) hydrolyzes glucuronidated metabolites to their toxic
form in intestines, resulting in intestinal damage. The development of a method to inhibit βG …
form in intestines, resulting in intestinal damage. The development of a method to inhibit βG …
β-Glucuronidase-Activated Bioluminescence Probe for In Vivo Tumor Imaging
L Yang, X Sun, L Xu, X Cheng, X Liu, Y Deng… - Analytical …, 2023 - ACS Publications
β-Glucuronidase (GLU) is a hallmark enzyme for many malignant tumors, but
bioluminescence (BL) probes that enable GLU imaging in vivo have not been reported …
bioluminescence (BL) probes that enable GLU imaging in vivo have not been reported …
Translocator protein and new targets for neuroinflammation
M Herrera-Rivero, MT Heneka… - Clinical and Translational …, 2015 - Springer
The mitochondrial translocator protein (18 kDa; TSPO) is involved in a wide array of
physiological processes importantly including cholesterol transport, steroidogenesis and …
physiological processes importantly including cholesterol transport, steroidogenesis and …
[HTML][HTML] New molecular targets for PET and SPECT imaging in neurodegenerative diseases
M Benadiba, G Luurtsema, L Wichert-Ana… - Brazilian Journal of …, 2012 - SciELO Brasil
The pathophysiology of neurodegenerative diseases (ND) such as Alzheimer's disease (AD)
and Parkinson's disease (PD) has not yet been completely elucidated. However, in the past …
and Parkinson's disease (PD) has not yet been completely elucidated. However, in the past …
[HTML][HTML] The place of PET to assess new therapeutic effectiveness in neurodegenerative diseases
AC Dupont, B Largeau, D Guilloteau… - Contrast Media & …, 2018 - hindawi.com
In vivo exploration of neurodegenerative diseases by positron emission tomography (PET)
imaging has matured over the last 20 years, using dedicated radiopharmaceuticals targeting …
imaging has matured over the last 20 years, using dedicated radiopharmaceuticals targeting …