[HTML][HTML] Radiopharmaceuticals for PET and SPECT imaging: a literature review over the last decade
G Crișan, NS Moldovean-Cioroianu… - International Journal of …, 2022 - mdpi.com
Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …
imaging of several metabolic processes, blood flow measurements, regional chemical …
18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography
S Preshlock, M Tredwell, V Gouverneur - Chemical reviews, 2016 - ACS Publications
Diverse radiochemistry is an essential component of nuclear medicine; this includes
imaging techniques such as positron emission tomography (PET). As such, PET can track …
imaging techniques such as positron emission tomography (PET). As such, PET can track …
Microglial activation and tau propagate jointly across Braak stages
Compelling experimental evidence suggests that microglial activation is involved in the
spread of tau tangles over the neocortex in Alzheimer's disease (AD). We tested the …
spread of tau tangles over the neocortex in Alzheimer's disease (AD). We tested the …
18F-MK-6240 PET for early and late detection of neurofibrillary tangles
Braak stages of tau neurofibrillary tangle accumulation have been incorporated in the
criteria for the neuropathological diagnosis of Alzheimer's disease. It is expected that Braak …
criteria for the neuropathological diagnosis of Alzheimer's disease. It is expected that Braak …
Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: phase 3 study
Background Evaluation of brain β‐amyloid by positron emission tomography (PET) imaging
can assist in the diagnosis of Alzheimer disease (AD) and other dementias. Methods Open …
can assist in the diagnosis of Alzheimer disease (AD) and other dementias. Methods Open …
Appropriate use criteria for amyloid PET: a report of the Amyloid Imaging Task Force, the Society of Nuclear Medicine and Molecular Imaging, and the Alzheimer's …
KA Johnson, S Minoshima, NI Bohnen… - Alzheimer's & …, 2013 - Elsevier
Positron emission tomography (PET) of brain amyloid β is a technology that is becoming
more available, but its clinical utility in medical practice requires careful definition. To …
more available, but its clinical utility in medical practice requires careful definition. To …
[HTML][HTML] Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain
KP Ng, TA Pascoal, S Mathotaarachchi… - Alzheimer's research & …, 2017 - Springer
Background 18 F-THK5351 is a quinoline-derived tau imaging agent with high affinity to
paired helical filaments (PHF). However, high levels of 18 F-THK5351 retention in brain …
paired helical filaments (PHF). However, high levels of 18 F-THK5351 retention in brain …
APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles
Animal studies suggest that the apolipoprotein E ε4 (APOE ε4) allele is a culprit of early
microglial activation in Alzheimer's disease (AD). Here, we tested the association between …
microglial activation in Alzheimer's disease (AD). Here, we tested the association between …
Brain PET in the diagnosis of Alzheimer's disease
C Marcus, E Mena, RM Subramaniam - Clinical nuclear medicine, 2014 - journals.lww.com
Objectives The aim of this article was to review the current role of brain PET in the diagnosis
of Alzheimer dementia. The characteristic patterns of glucose metabolism on brain FDG-PET …
of Alzheimer dementia. The characteristic patterns of glucose metabolism on brain FDG-PET …
Association of apolipoprotein E ε4 with medial temporal tau independent of amyloid-β
Importance Apolipoprotein E ε4 (APOEε4) is the single most important genetic risk factor for
Alzheimer disease. WhileAPOEε4is associated with increased amyloid-β burden, its …
Alzheimer disease. WhileAPOEε4is associated with increased amyloid-β burden, its …