Nanomaterials for in vivo imaging

BR Smith, SS Gambhir - Chemical reviews, 2017 - ACS Publications
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

[HTML][HTML] Photoacoustic clinical imaging

I Steinberg, DM Huland, O Vermesh, HE Frostig… - Photoacoustics, 2019 - Elsevier
Photoacoustic is an emerging biomedical imaging modality, which allows imaging optical
absorbers in the tissue by acoustic detectors (light in-sound out). Such a technique has an …

[HTML][HTML] Improving conventional enhanced permeability and retention (EPR) effects; what is the appropriate target?

H Kobayashi, R Watanabe, PL Choyke - Theranostics, 2014 - ncbi.nlm.nih.gov
Nano-sized therapeutic agents have several advantages over low molecular weight agents
such as a larger loading capacity, the ability to protect the payload until delivery, more …

Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

Noninvasive imaging of nanomedicines and nanotheranostics: principles, progress, and prospects

S Kunjachan, J Ehling, G Storm, F Kiessling… - Chemical …, 2015 - ACS Publications
Nanomedicine is defined as “the application of nanotechnology to medicine, including the
use of nanometer-sized carrier materials for facilitating disease diagnosis, disease treatment …

[HTML][HTML] Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery

V Paefgen, D Doleschel, F Kiessling - Frontiers in pharmacology, 2015 - frontiersin.org
Ultrasound (US) is one of the most frequently used diagnostic methods. It is a non-invasive,
comparably inexpensive imaging method with a broad spectrum of applications, which can …

Breast ultrasonography: state of the art

RJ Hooley, LM Scoutt, LE Philpotts - Radiology, 2013 - pubs.rsna.org
Ultrasonography (US) is an indispensable tool in breast imaging and is complementary to
both mammography and magnetic resonance (MR) imaging of the breast. Advances in US …

Recent progress in nanomedicine: therapeutic, diagnostic and theranostic applications

LY Rizzo, B Theek, G Storm, F Kiessling… - Current opinion in …, 2013 - Elsevier
Highlights▶ Nanomedicines can be used for therapeutic, diagnostic and theranostic
applications.▶ Nanotherapeutics aims to improve the balance between efficacy and …

Passive versus active tumor targeting using RGD-and NGR-modified polymeric nanomedicines

S Kunjachan, R Pola, F Gremse, B Theek, J Ehling… - Nano …, 2014 - ACS Publications
Enhanced permeability and retention (EPR) and the (over-) expression of angiogenesis-
related surface receptors are key features of tumor blood vessels. As a consequence, EPR …

Toward drug release using polymer mechanochemical disulfide scission

Z Shi, J Wu, Q Song, R Göstl… - Journal of the American …, 2020 - ACS Publications
Traditional pharmacotherapy suffers from multiple drawbacks that hamper patient treatment,
such as the buildup of antibiotic resistances or low drug selectivity and toxicity during …