The shortly upcoming 5th edition of the World Health Organization Classification of Tumors
of the Central Nervous System is bringing extensive changes in the terminology of diffuse …

Glioblastoma multiforme (GBM) is the deadliest type of brain tumor, affecting approximately
three in 100,000 adults annually. Positron emission tomography (PET) imaging provides an …

Objectives Intra-individual spatial overlap analysis of tumor volumes assessed by MRI, the
amino acid PET tracer [18F]-FET and the nucleoside PET tracer [18F]-FLT in high-grade …

Purpose Positron emission tomography (PET)/computed tomography (CT) has become a
critical tool in clinical oncology with an expanding role in guiding radiation treatment …

Ongoing research on malignant and normal cell biology has substantially enhanced the
understanding of the biology of cancer and carcinogenesis. This has led to the development …

The vast majority of malignant gliomas relapse after surgery and standard radio-
chemotherapy. Novel molecular and cellular therapies are thus being developed, targeting …

Background Polyploid giant cancer cells (PGCCs) contribute to solid tumor heterogeneity.
This study investigated the relationships among PGCCs numbers, vasculogenic mimicry …

Simple Summary To test the hypothesis that quantitative magnetic resonance relaxometry
reflects glioma tumor load within tissue and that it can be an imaging surrogate for …

Purpose In this study, kinetic parameters of the cellular proliferation tracer 18 F-3′-deoxy-
3′-fluoro-l-thymidine (FLT) and the amino acid probe 3, 4-dihydroxy-6-18 F-fluoro-l …

Brain neoplasms constitute a group of tumors with discrete differentiation grades, and
therefore, course of disease and prognosis. Magnetic resonance imaging (MRI) remains the …