The autonomic nervous system and heart failure
VG Florea, JN Cohn - Circulation research, 2014 - Am Heart Assoc
The pathophysiology of heart failure (HF) is characterized by hemodynamic abnormalities
that result in neurohormonal activation and autonomic imbalance with increase in …
that result in neurohormonal activation and autonomic imbalance with increase in …
[HTML][HTML] Critical neurotransmitters in the neuroimmune network
TW Hodo, MTP De Aquino, A Shimamoto… - Frontiers in …, 2020 - frontiersin.org
Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …
express an extensive network of cell communication modes, including a vast repertoire of …
Nuclear imaging of the cardiac sympathetic nervous system: a disease-specific interpretation in heart failure
Abnormalities in the cardiac sympathetic nervous system have been documented in various
heart diseases and have been directly implicated in their pathogenesis and disease …
heart diseases and have been directly implicated in their pathogenesis and disease …
Radiopharmaceutical tracers for cardiac imaging
O Manabe, T Kikuchi, AJHA Scholte… - Journal of Nuclear …, 2018 - Elsevier
Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide.
Nuclear myocardial perfusion imaging with either single-photon emission computed …
Nuclear myocardial perfusion imaging with either single-photon emission computed …
Retention kinetics of the 18F-labeled sympathetic nerve PET tracer LMI1195: comparison with 11C-hydroxyephedrine and 123I-MIBG
RA Werner, C Rischpler, D Onthank… - Journal of Nuclear …, 2015 - Soc Nuclear Med
18F-N-[3-bromo-4-(3-fluoro-propoxy)-benzyl]-guanidine (18F-LMI1195) is a new PET tracer
designed for noninvasive assessment of sympathetic innervation of the heart. The 18F label …
designed for noninvasive assessment of sympathetic innervation of the heart. The 18F label …
The future of cardiac molecular imaging
Molecular imaging with positron emission tomography (PET) and single-photon emission
computed tomography (SPECT) serves numerous applications in clinical cardiology and …
computed tomography (SPECT) serves numerous applications in clinical cardiology and …
Targeting the autonomic nervous system: measuring autonomic function and novel devices for heart failure management
HC Patel, SD Rosen, A Lindsay, C Hayward… - International journal of …, 2013 - Elsevier
Neurohumoral activation, in which enhanced activity of the autonomic nervous system (ANS)
is a key component, plays a pivotal role in heart failure. The neurohumoral system affects …
is a key component, plays a pivotal role in heart failure. The neurohumoral system affects …
Towards a clearer view of sympathetic innervation of cardiac and skeletal muscles
A Di Bona, V Vita, I Costantini, T Zaglia - Progress in Biophysics and …, 2020 - Elsevier
It is well appreciated that autonomic neurons have a central role in the homeostatic
regulation of organs and systems and participate to the pathogenesis of several disease …
regulation of organs and systems and participate to the pathogenesis of several disease …
[HTML][HTML] Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity—Introducing High NET Affinity PET Probe 18F-AF78
Background: Radiolabeled agents that are substrates for the norepinephrine transporter
(NET) can be used to quantify cardiac sympathetic nervous conditions and have been …
(NET) can be used to quantify cardiac sympathetic nervous conditions and have been …
[HTML][HTML] SPECT vs. PET in cardiac innervation imaging: clash of the titans
Purpose We aim to provide an overview of the conventional single photon emission
computed tomography (SPECT) and emerging positron emission tomography (PET) …
computed tomography (SPECT) and emerging positron emission tomography (PET) …