Cardiac PET perfusion tracers: current status and future directions
J Maddahi, RRS Packard - Seminars in nuclear medicine, 2014 - Elsevier
PET myocardial perfusion imaging (MPI) is increasingly being used for noninvasive
detection and evaluation of coronary artery disease. However, the widespread use of PET …
detection and evaluation of coronary artery disease. However, the widespread use of PET …
PET and SPECT tracers for myocardial perfusion imaging
Coronary artery disease has been the leading cause of death since the 1960s, which has
motivated the research and development of myocardial perfusion imaging (MPI) agents for …
motivated the research and development of myocardial perfusion imaging (MPI) agents for …
Imaging cell death
AA Neves, KM Brindle - Journal of Nuclear Medicine, 2014 - Soc Nuclear Med
There is currently a need for imaging methods capable of detecting cell death in tissues and
the early onset of tumor cell death resulting from therapy. However, to date, no probe has …
the early onset of tumor cell death resulting from therapy. However, to date, no probe has …
Absolute quantitation of myocardial blood flow in human subjects with or without myocardial ischemia using dynamic flurpiridaz F 18 PET
RRS Packard, SC Huang, M Dahlbom… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Absolute quantitation of myocardial blood flow (MBF) by PET is an established method of
analyzing coronary artery disease (CAD) but subject to the various shortcomings of …
analyzing coronary artery disease (CAD) but subject to the various shortcomings of …
Longitudinal 18F-FDG PET imaging in a rat model of autoimmune myocarditis
RA Werner, H Wakabayashi, J Bauer… - European Heart …, 2019 - academic.oup.com
Aims Although mortality rate is very high, diagnosis of acute myocarditis remains
challenging with conventional tests. We aimed to elucidate the potential role of longitudinal …
challenging with conventional tests. We aimed to elucidate the potential role of longitudinal …
[HTML][HTML] Moving into the next era of PET myocardial perfusion imaging: introduction of novel 18F-labeled tracers
The heart failure epidemic continues to rise with coronary artery disease as one of its main
causes. Novel concepts for risk stratification to guide the referring cardiologist towards …
causes. Novel concepts for risk stratification to guide the referring cardiologist towards …
Targeted imaging for cell death in cardiovascular disorders
A Shekhar, P Heeger, C Reutelingsperger… - JACC: Cardiovascular …, 2018 - jacc.org
Cell death is desirable in cancer cells and undesirable in organs with limited regenerative
potential, like the heart. Cell death comes in many forms, but only apoptosis and to a lesser …
potential, like the heart. Cell death comes in many forms, but only apoptosis and to a lesser …
Avenues to molecular imaging of dying cells: Focus on cancer
AA Rybczynska, HH Boersma… - Medicinal research …, 2018 - Wiley Online Library
Successful treatment of cancer patients requires balancing of the dose, timing, and type of
therapeutic regimen. Detection of increased cell death may serve as a predictor of the …
therapeutic regimen. Detection of increased cell death may serve as a predictor of the …
11C-methionine PET of myocardial inflammation in a rat model of experimental autoimmune myocarditis
Y Maya, RA Werner, C Schütz… - Journal of nuclear …, 2016 - Soc Nuclear Med
Myocarditis represents a major cause of dilated cardiomyopathy and sudden cardiac death
in younger adults. Currently, definitive diagnosis of myocarditis requires endomyocardial …
in younger adults. Currently, definitive diagnosis of myocarditis requires endomyocardial …
Development of mitochondria-targeted small-molecule dyes for myocardial PET and fluorescence bimodal imaging
L Zheng, Z Wang, X Zhang, Y Zhou, A Ji… - Journal of Medicinal …, 2021 - ACS Publications
Mitochondria-targeting positron emission tomography (PET) and fluorescent dual-modal
probes are rarely reported. As one of the most promising lipophilic cations, F16 and its …
probes are rarely reported. As one of the most promising lipophilic cations, F16 and its …