PET myocardial perfusion imaging (MPI) is increasingly being used for noninvasive
detection and evaluation of coronary artery disease. However, the widespread use of PET …

Coronary artery disease has been the leading cause of death since the 1960s, which has
motivated the research and development of myocardial perfusion imaging (MPI) agents for …

There is currently a need for imaging methods capable of detecting cell death in tissues and
the early onset of tumor cell death resulting from therapy. However, to date, no probe has …

Absolute quantitation of myocardial blood flow (MBF) by PET is an established method of
analyzing coronary artery disease (CAD) but subject to the various shortcomings of …

Aims Although mortality rate is very high, diagnosis of acute myocarditis remains
challenging with conventional tests. We aimed to elucidate the potential role of longitudinal …

The heart failure epidemic continues to rise with coronary artery disease as one of its main
causes. Novel concepts for risk stratification to guide the referring cardiologist towards …

Cell death is desirable in cancer cells and undesirable in organs with limited regenerative
potential, like the heart. Cell death comes in many forms, but only apoptosis and to a lesser …

Successful treatment of cancer patients requires balancing of the dose, timing, and type of
therapeutic regimen. Detection of increased cell death may serve as a predictor of the …

Myocarditis represents a major cause of dilated cardiomyopathy and sudden cardiac death
in younger adults. Currently, definitive diagnosis of myocarditis requires endomyocardial …

Mitochondria-targeting positron emission tomography (PET) and fluorescent dual-modal
probes are rarely reported. As one of the most promising lipophilic cations, F16 and its …