[HTML][HTML] Imaging metabolic heterogeneity in cancer
D Sengupta, G Pratx - Molecular cancer, 2016 - Springer
As our knowledge of cancer metabolism has increased, it has become apparent that cancer
metabolic processes are extremely heterogeneous. The reasons behind this heterogeneity …
metabolic processes are extremely heterogeneous. The reasons behind this heterogeneity …
[HTML][HTML] Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene
A Hall, KD Meyle, MK Lange, M Klima, M Sanderhoff… - Oncotarget, 2013 - ncbi.nlm.nih.gov
Oncogene addiction describes how cancer cells exhibit dependence on single oncogenes
to escape apoptosis and senescence. While oncogene addiction constitutes the basis for …
to escape apoptosis and senescence. While oncogene addiction constitutes the basis for …
Emerging technologies for decentralized production of PET tracers
PY Keng, M Esterby, RM van Dam - … emission tomography-current …, 2012 - books.google.com
The use of Positron Emission Tomography (PET) to monitor biological processes in vivo
(Michael E. Phelps 2000) has seen dramatic growth and acceptance in the research …
(Michael E. Phelps 2000) has seen dramatic growth and acceptance in the research …
Batch-reactor microfluidic device: first human use of a microfluidically produced PET radiotracer
A Lebedev, R Miraghaie, K Kotta, CE Ball, J Zhang… - Lab on a Chip, 2013 - pubs.rsc.org
The very first microfluidic device used for the production of 18F-labeled tracers for clinical
research is reported along with the first human Positron Emission Tomography scan …
research is reported along with the first human Positron Emission Tomography scan …
On chip two-photon metabolic imaging for drug toxicity testing
We have developed a microfluidic system suitable to be incorporated with a metabolic
imaging method to monitor the drug response of cells cultured on a chip. The cells were …
imaging method to monitor the drug response of cells cultured on a chip. The cells were …
Optimization of microfluidic PET tracer synthesis with Cerenkov imaging
AA Dooraghi, PY Keng, S Chen, MR Javed… - Analyst, 2013 - pubs.rsc.org
Microfluidic technologies provide an attractive platform for the synthesis of radiolabeled
compounds. Visualization of radioisotopes on chip is critical for synthesis optimization and …
compounds. Visualization of radioisotopes on chip is critical for synthesis optimization and …
High-resolution radioluminescence microscopy of 18F-FDG uptake by reconstructing the β-ionization track
Radioluminescence microscopy is a new method for imaging radionuclide uptake by single
live cells with a fluorescence microscope. Here, we report a particle-counting scheme that …
live cells with a fluorescence microscope. Here, we report a particle-counting scheme that …
Microfluidic radiobioassays: a radiometric detection tool for understanding cellular physiology and pharmacokinetics
Z Liu, X Lan - Lab on a Chip, 2019 - pubs.rsc.org
The investigation of molecular uptake and its kinetics in cells is valuable for understanding
the cellular physiological status, the observation of drug interventions, and the development …
the cellular physiological status, the observation of drug interventions, and the development …
Development of radiodetection systems towards miniaturised quality control of PET and SPECT radiopharmaceuticals
MP Taggart, MD Tarn, MMN Esfahani, DM Schofield… - Lab on a Chip, 2016 - pubs.rsc.org
The ability to detect radiation in microfluidic devices is important for the on-chip analysis of
radiopharmaceuticals, but previously reported systems have largely suffered from various …
radiopharmaceuticals, but previously reported systems have largely suffered from various …
Betabox: a beta particle imaging system based on a position sensitive avalanche photodiode
AA Dooraghi, NT Vu, RW Silverman… - Physics in Medicine …, 2013 - iopscience.iop.org
A beta camera has been developed that allows planar imaging of the spatial and temporal
distribution of beta particles using a 14× 14 mm 2 position sensitive avalanche photodiode …
distribution of beta particles using a 14× 14 mm 2 position sensitive avalanche photodiode …