The positron emission tomography (PET) molecular imaging technique has gained its
universal value as a remarkable tool for medical diagnosis and biomedical research …

The presence of positron emission tomography (PET) centers at most major hospitals
worldwide, along with the improvement of PET scanner sensitivity and the introduction of …

Metabolomics research has the potential to provide biomarkers for the detection of disease,
for subtyping complex disease populations, for monitoring disease progression and therapy …

Tumor cells have an increased nutritional demand for amino acids (AAs) to satisfy their rapid
proliferation. Positron-emitting nuclide labeled AAs are interesting probes and are of great …

The metabolic rewiring of tumor cells and immune cells has been viewed as a promising
source of novel drug targets. Many of the molecular pathways implicated in rheumatoid …

Brain tumors are one of the most challenging disorders encountered, and early and accurate
diagnosis is essential for the management and treatment of these tumors. In this article …

The different concepts realized for the synthesis of 11C‐and 18F‐labelled amino acids are
summarized. Carbon‐11 enables principally authentic radiolabelling of natural occurring …

Although 11 C-labelled sulfur-containing amino acids (SAAs) including L-methyl-[11 C]
methionine and S-[11 C]-methyl-L-cysteine, are attractive tracers for glioma positron …

Introduction N-position radiolabeled amino acids, such as N-(2-[18 F] fluoropropionyl)-L-
methionine ([18 F] FPMET) as a derivative of L-methionine (MET), can potentially serve as a …

We have previously reported that N-(2-[18F] fluoropropionyl)-l-methionine ([18F] FPMET)
selectively accumulates in tumors. However, due to the poor pharmacokinetics of [18F] …