Recent progress of cell-penetrating peptides as new carriers for intracellular cargo delivery

F Wang, Y Wang, X Zhang, W Zhang, S Guo… - Journal of Controlled …, 2014 - Elsevier
The plasma membrane as a selectively permeable barrier of living cells is essential to cell
survival and function. In many cases, however, the efficient passage of exogenous bioactive …

[HTML][HTML] Redesigning of cell-penetrating peptides to improve their efficacy as a drug delivery system

I Szabó, M Yousef, D Soltész, C Bató, G Mező… - Pharmaceutics, 2022 - mdpi.com
Cell-penetrating peptides (CPP) are promising tools for the transport of a broad range of
compounds into cells. Since the discovery of the first members of this peptide family, many …

Molecular machines open cell membranes

V García-López, F Chen, LG Nilewski, G Duret… - Nature, 2017 - nature.com
Beyond the more common chemical delivery strategies, several physical techniques are
used to open the lipid bilayers of cellular membranes. These include using electric and …

Advancement in integrin facilitated drug delivery

D Arosio, C Casagrande - Advanced Drug Delivery Reviews, 2016 - Elsevier
The research of integrin-targeted anticancer agents has recorded important advancements
in ingenious design of delivery systems, based either on the prodrug approach, or on …

Physalis mottle virus-like nanoparticles for targeted cancer imaging

H Hu, H Masarapu, Y Gu, Y Zhang, X Yu… - … applied materials & …, 2019 - ACS Publications
One of the greatest challenges in nanomedicine is the low efficiency with which
nanoparticles are delivered to lesions such as tumors in vivo. Here, we show that Physalis …

[HTML][HTML] Cell-penetrating peptides (CPPs) as therapeutic and diagnostic agents for cancer

RA Bottens, T Yamada - Cancers, 2022 - mdpi.com
Simple Summary Crossing biological barriers is often required for drug delivery. Cell-
penetrating peptides (CPPs) are short strands of amino acids that have been widely used as …

[HTML][HTML] Biocompatibility of novel type I collagen purified from tilapia fish scale: an in vitro comparative study

J Tang, T Saito - BioMed research international, 2015 - hindawi.com
Type I collagen (COL-1) is the prevailing component of the extracellular matrix in a number
of tissues including skin, ligament, cartilage, bone, and dentin. It is the most widely used …

Prospective cancer therapies using stimuli‐responsive DNA nanostructures

I Seitz, A Shaukat, K Nurmi, H Ijäs… - Macromolecular …, 2021 - Wiley Online Library
Nanostructures based on DNA self‐assembly present an innovative way to address the
increasing need for target‐specific delivery of therapeutic molecules. Currently, most of the …

[HTML][HTML] Optical imaging probes in oncology

C Martelli, AL Dico, C Diceglie, G Lucignani… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cancer is a complex disease, characterized by alteration of different physiological molecular
processes and cellular features. Keeping this in mind, the possibility of early identification …

Brush border enzyme-cleavable linkers: Evaluation for reducing renal uptake of radiolabeled prostate-specific membrane antigen inhibitors

G Vaidyanathan, CM Kang, D McDougald… - Nuclear medicine and …, 2018 - Elsevier
Introduction Radiolabeled, low-molecular-weight prostate-specific membrane antigen
(PSMA) inhibitors based on the Glu-ureido pharmacophore show promise for the detection …