FDG-PET, combined with CT, is nowadays getting more and more relevant for the diagnosis
of several infectious and inflammatory diseases and particularly for therapy monitoring …

Macrophages play a key role in the pathophysiology of rheumatoid arthritis (RA). Notably,
positive correlations have been reported between synovial macrophage infiltration and …

Objective To develop evidence-based recommendations on the use of imaging of the joints
in the clinical management of rheumatoid arthritis (RA). Methods The task force comprised …

TNF is a central cytokine in the pathogenesis of rheumatoid arthritis (RA). Elevated level of
TNF causes local inflammation that affects immune cells and fibroblast-like synoviocytes …

The technology behind positron emission tomography (PET) and the most widely used
tracer, 2-deoxy-2-[18F] fluoro-D-glucose (FDG), were both conceived in the 1970s, but the …

FDG is a tracer for visualizing glucose metabolism. PET/CT using FDG is widely used for the
diagnosis of cancer, because glycolysis is elevated in cancer cells. Similarly, active …

Rheumatic diseases are various painful conditions that affect joints, bones, cartilage,
tendons, ligaments, and muscles. Arthritis is a typical condition of rheumatic disease …

Advanced imaging techniques may enable early diagnosis and monitoring of therapy in
various rheumatic diseases. To prevent irreversible tissue damage, inflammatory rheumatic …

Arthritis and other rheumatic disorders are very frequent in the general population and
responsible for a huge physical and disability burden to affected patients as well as a major …

Imaging techniques such as ultrasonography and MRI have gained ground in the diagnosis
and management of inflammatory arthritis, as these imaging modalities allow a sensitive …