Maintaining research and development (R&D) productivity at a sustainable level is one of
the main challenges currently facing the pharmaceutical industry. In this article, we discuss …

As immunogenic cell death (ICD) inducers initiating antitumor immune responses, certain
chemotherapeutic drugs have shown considerable potential to reverse the …

The discovery of the vitamin D endocrine system and a receptor for the hormonal form, 1α,
25-dihydroxyvitamin D3, has brought a new understanding of the relationship between …

Despite dramatic advances in the molecular pathogenesis of disease, translation of basic
biomedical research into safe and effective clinical applications remains a slow, expensive …

Abstract Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more
realistically compared to many animal models and conventional two‐dimensional cell …

Recently, various second near‐infrared window (NIR‐II, 1000–1700 nm) fluorophores have
been synthesized for in vivo imaging with nonradiation, high resolution, and low …

Simple Summary Colorectal cancer is one of the most common solid tumors in the
developed world. Although there have being many advances in treatment options in recent …

The endothelin axis, recognized for its vasoconstrictive action, plays a central role in the
pathology of pulmonary arterial hypertension (PAH). Treatment with approved endothelin …

The p53 transcription factor confers its potent tumor suppressor functions primarily through
the regulation of a large network of target genes. The recent explosion of next generation …

While cancer remains the major cause of death worldwide, nanomaterial (NM)-based
diagnosis and treatment modalities are showing remarkable potential to better tackle clinical …