Radiopharmaceutical chemistry for positron emission tomography

Z Li, PS Conti - Advanced drug delivery reviews, 2010 - Elsevier
Molecular imaging is an emerging technology that allows the visualization of interactions
between molecular probes and biological targets. Molecules that either direct or are subject …

Electrochemical synthesis in microreactors

K Watts, A Baker, T Wirth - Journal of Flow Chemistry, 2015 - akjournals.com
Electrochemical Synthesis in Microreactors Page 1 Electrochemical Synthesis in Microreactors
Kevin Watts, Alastair Baker and Thomas Wirth* School of Chemistry, Cardiff University, Park …

Micro-chemical synthesis of molecular probes on an electronic microfluidic device

PY Keng, S Chen, H Ding, S Sadeghi… - Proceedings of the …, 2012 - National Acad Sciences
We have developed an all-electronic digital microfluidic device for microscale chemical
synthesis in organic solvents, operated by electrowetting-on-dielectric (EWOD). As an …

Integrating machine learning and digital microfluidics for screening experimental conditions

F Ahmadi, M Simchi, JM Perry, S Frenette, H Benali… - Lab on a Chip, 2023 - pubs.rsc.org
Digital microfluidics (DMF) has the signatures of an ideal liquid handling platform–as shown
through almost two decades of automated biological and chemical assays. However, in the …

Microfluidics in radiopharmaceutical chemistry

G Pascali, P Watts, PA Salvadori - Nuclear medicine and biology, 2013 - Elsevier
The increased demand for molecular imaging tracers useful in assessing and monitoring
diseases has stimulated research towards more efficient and flexible radiosynthetic routes …

[HTML][HTML] Performing radiosynthesis in microvolumes to maximize molar activity of tracers for positron emission tomography

M Sergeev, M Lazari, F Morgia, J Collins… - Communications …, 2018 - nature.com
Positron emission tomography (PET) is a molecular diagnostic imaging technology to
quantitatively visualize biological processes in vivo. For many applications, including …

[HTML][HTML] Microfluidic synthesis of radiotracers: Recent developments and commercialization prospects

M Mc Veigh, LM Bellan - Lab on a Chip, 2024 - pubs.rsc.org
Positron emission tomography (PET) is a powerful diagnostic tool that holds incredible
potential for clinicians to track a wide variety of biological processes using specialized …

[HTML][HTML] Microfluidics: a groundbreaking technology for PET tracer production?

C Rensch, A Jackson, S Lindner, R Salvamoser… - Molecules, 2013 - mdpi.com
Application of microfluidics to Positron Emission Tomography (PET) tracer synthesis has
attracted increasing interest within the last decade. The technical advantages of …

Ultra-compact, automated microdroplet radiosynthesizer

J Wang, PH Chao, RM van Dam - Lab on a Chip, 2019 - pubs.rsc.org
Application of microfluidics offers numerous advantages in the field of radiochemistry and
could enable dramatic reductions in the cost of producing radiotracers for positron emission …

Recent Advances in Microfluidic Devices for the Radiosynthesis of PET‐imaging Probes

H Elkawad, Y Xu, M Tian, C Jin… - Chemistry–An Asian …, 2022 - Wiley Online Library
In order to accommodate the growing demand for positron emission tomography (PET), it
will be necessary to create innovative radiochemical and engineering technologies to …