[HTML][HTML] Astatine-211 based radionuclide therapy: Current clinical trial landscape

P Albertsson, T Bäck, K Bergmark, A Hallqvist… - Frontiers in …, 2023 - frontiersin.org
Astatine-211 (211At) has physical properties that make it one of the top candidates for use
as a radiation source for alpha particle-based radionuclide therapy, also referred as targeted …

GD2-targeted immunotherapy and radioimmunotherapy

K Dobrenkov, NKV Cheung - Seminars in oncology, 2014 - Elsevier
Ganglioside GD2 is a tumor-associated surface antigen found in a broad spectrum of human
cancers and stem cells. They include pediatric embryonal tumors (neuroblastoma …

[HTML][HTML] Phase 1 study of intraventricular 131I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies

K Kramer, N Pandit-Taskar, BH Kushner… - Journal of Hematology & …, 2022 - Springer
Background The prognosis for metastatic and recurrent tumors of the central nervous system
(CNS) remains dismal, and the need for newer therapeutic targets and modalities is critical …

IntraOmmaya compartmental radioimmunotherapy using 131I-omburtamab—pharmacokinetic modeling to optimize therapeutic index

RS Yerrabelli, P He, EK Fung, K Kramer… - European journal of …, 2021 - Springer
Purpose Radioimmunotherapy (RIT) delivered through the cerebrospinal fluid (CSF) has
been shown to be a safe and promising treatment for leptomeningeal metastases …

[HTML][HTML] Modulation of solute diffusivity in brain tissue as a novel mechanism of transcranial direct current stimulation (tDCS)

Y Xia, W Khalid, Z Yin, G Huang, M Bikson, BM Fu - Scientific Reports, 2020 - nature.com
The breadth of brain disorders and functions reported responsive to transcranial direct
current stimulation (tDCS) suggests a generalizable mechanism of action. Prior efforts …

[BOOK][B] Molecular, cellular, and tissue engineering

JD Bronzino, DR Peterson - 2018 - api.taylorfrancis.com
Known as the bible of biomedical engineering, The Biomedical Engineering Handbook,
Fourth Edition, sets the standard against which all other references of this nature are …

[HTML][HTML] Pharmacokinetic delivery and metabolizing rate of nicardipine incorporated in hydrophilic and hydrophobic cyclodextrins using two-compartment …

S Shityakov, C Förster - The Scientific World Journal, 2016 - hindawi.com
The dispersion routes of cyclodextrin complexes with nicardipine (NC), such as hydrophilic
hydroxypropyl--cyclodextrin (NC/HP CD) and hydrophobic triacetyl--cyclodextrin (NC/TA …

[HTML][HTML] Enhanced transport capabilities via nanotechnologies: impacting bioefficacy, controlled release strategies, and novel chaperones

T Panagiotou, RJ Fisher - Journal of drug delivery, 2011 - hindawi.com
Emerging nanotechnologies have, and will continue to have, a major impact on the
pharmaceutical industry. Their influence on a drug's life cycle, inception to delivery, is rapidly …

Two-compartment model of radioimmunotherapy delivered through cerebrospinal fluid

P He, K Kramer, P Smith-Jones, P Zanzonico… - European journal of …, 2011 - Springer
Abstract Purpose Radioimmunotherapy (RIT) using 131 I-3F8 injected into cerebrospinal
fluid (CSF) was a safe modality for the treatment of leptomeningeal metastases (JCO, 25 …

[BOOK][B] Handbook of Nuclear Medicine and Molecular Imaging for Physicists: Modelling, Dosimetry and Radiation Protection, Volume II

M Ljungberg - 2021 - api.taylorfrancis.com
Mathematical modelling is an important part of nuclear medicine. Therefore, several
chapters of this book have been dedicated towards describing this topic. In these chapters …