The principles and applications of avidin-based nanoparticles in drug delivery and diagnosis
A Jain, K Cheng - Journal of controlled release, 2017 - Elsevier
Avidin-biotin interaction is one of the strongest non-covalent interactions in the nature.
Avidin and its analogues have therefore been extensively utilized as probes and affinity …
Avidin and its analogues have therefore been extensively utilized as probes and affinity …
[HTML][HTML] An update on in vivo imaging of extracellular vesicles as drug delivery vehicles
Extracellular vesicles (EVs) are currently being considered as promising drug delivery
vehicles. EVs are naturally occurring vesicles that exhibit many characteristics favorable to …
vehicles. EVs are naturally occurring vesicles that exhibit many characteristics favorable to …
Quantitative analysis of tissue distribution of the B16BL6-derived exosomes using a streptavidin-lactadherin fusion protein and iodine-125-labeled biotin derivative …
M Morishita, Y Takahashi, M Nishikawa, K Sano… - Journal of …, 2015 - Elsevier
We previously succeeded in the visualization of tissue distribution of B16BL6 cells-derived
exosomes by labeling with Gaussia luciferase (gLuc)-LA, a fusion protein of gLuc (a reporter …
exosomes by labeling with Gaussia luciferase (gLuc)-LA, a fusion protein of gLuc (a reporter …
[HTML][HTML] The role of imaging biomarkers to guide pharmacological interventions targeting tumor hypoxia
B Gallez - Frontiers in pharmacology, 2022 - frontiersin.org
Hypoxia is a common feature of solid tumors that contributes to angiogenesis, invasiveness,
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …
[HTML][HTML] Radionuclide imaging and therapy directed towards the tumor microenvironment: A multi-cancer approach for personalized medicine
CD van der Heide, SU Dalm - European Journal of Nuclear Medicine and …, 2022 - Springer
Targeted radionuclide theranostics is becoming more and more prominent in clinical
oncology. Currently, most nuclear medicine compounds researched for cancer theranostics …
oncology. Currently, most nuclear medicine compounds researched for cancer theranostics …
Hypoxia-driven immunosuppression: a new reason to use thermal therapy in the treatment of cancer?
Hypoxia within the tumour microenvironment is correlated with poor treatment outcome after
radiation and chemotherapy, and with decreased overall survival in cancer patients. Several …
radiation and chemotherapy, and with decreased overall survival in cancer patients. Several …
18F-fluoromisonidazole PET uptake is correlated with hypoxia-inducible factor-1α expression in oral squamous cell carcinoma
J Sato, Y Kitagawa, Y Yamazaki, H Hata… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Hypoxia is a common feature of cancer and a prognostic factor for many types of cancer. 18F-
fluoromisonidazole (18F-FMISO) PET can detect tumor hypoxia noninvasively. Hypoxia …
fluoromisonidazole (18F-FMISO) PET can detect tumor hypoxia noninvasively. Hypoxia …
In vivo molecular imaging
H Saji - Biological and Pharmaceutical Bulletin, 2017 - jstage.jst.go.jp
In vivo molecular imaging is the visualization, characterization, and measurement of
biological processes at the molecular and cellular levels in humans and other living …
biological processes at the molecular and cellular levels in humans and other living …
Oroxylin A regulates glucose metabolism in response to hypoxic stress with the involvement of Hypoxia‐inducible factor‐1 in human hepatoma HepG2 cells
Q Dai, Q Yin, L Wei, Y Zhou, C Qiao… - Molecular …, 2016 - Wiley Online Library
Metabolic alteration in cancer cells is one of the most conspicuous characteristics that
distinguish cancer cells from normal cells. In this study, we investigated the influence and …
distinguish cancer cells from normal cells. In this study, we investigated the influence and …
Imaging the Hypoxic Tumor Microenvironment in Cancer Models
A Parihar, P Sharma, M Sharma, R Khan - Hypoxia in Cancer: Significance …, 2023 - Springer
In hypoxic condition oxygen supply is disrupted, and it happens in myocardial infarction,
stroke, or tumorous growth. If cells in normal tissue lose their oxygen supply abruptly, they …
stroke, or tumorous growth. If cells in normal tissue lose their oxygen supply abruptly, they …