Metabolic changes in cells that participate in inflammation, such as activated macrophages
and T-helper 17 cells, include a shift towards enhanced glucose uptake, glycolysis and …

An increasing number of studies show how changes in intracellular metabolic pathways
alter tumor and immune cell function. However, little information about metabolic changes in …

Objective Up‐regulation of glucose metabolism has been implicated not only in tumor cell
growth but also in immune cells upon activation. However, little is known about the …

Mitochondria are major energy-producing organelles that have central roles in cellular
metabolism. They also act as important signalling hubs, and their dynamic regulation in …

Swelling and the progressive destruction of articular cartilage are major characteristics of
rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial …

It has become clear that cancer is not merely a growth of autonomously proliferating cells,
but that other non‐malignant cell types are a functional part of the disease. Immune cells …

Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic
disruption that may be therapeutically targetable. Among them, glucose metabolism and …

TNF is a central cytokine in the pathogenesis of rheumatoid arthritis (RA). Elevated level of
TNF causes local inflammation that affects immune cells and fibroblast-like synoviocytes …

One of the most prominent cell populations playing a role in rheumatoid arthritis (RA) is
activated fibroblast-like synoviocytes. Among many other proteins, fibroblast-like …

Immunometabolism provides a new perspective on the pathogenesis of rheumatoid arthritis
(RA). In recent years, there have been investigations focusing on the role of intracellular …