Leukocyte-and platelet-rich plasma (L-PRP) contains high concentrations of platelet,
leukocytes and other bioactivities, which play an prominent role in both bone and soft tissue …

Osteoarthritis (OA) is a common disease associated with tissue inflammation, physical
disability and imbalanced homeostasis in cartilage. For advanced treatments, biological …

Bone tissue degeneration is an urgent clinical issue, making it a subject of intensive
research. Chronic skeletal disease forms can be prevalent, such as the age-related …

This study was undertaken to evaluate the role of collagen matrix to enhance platelet-rich
plasma (PRP) effects on pro-inflammatory cytokine-induced arthritic model. We have …

The aim of this study was to develop a new diagnostic and therapeutic approach for the
treatment of osteoporosis. Previously, we demonstrated that intraosseous transplantation of …

Aging and age-related changes impact the quality of life (QOL) in elderly with a decline in
movement, cognitive abilities and increased vulnerability towards age-related diseases …

Background Spinal cord injury (SCI) presents a significant challenge for the field of
neurotherapeutics. Stem cells have shown promise in replenishing the cells lost to the injury …

Inherited bone disorders account for about 10% of documented Mendelian disorders and
are associated with high financial burden. Their study requires osteoblasts which play a …

Aging is related to loss of functional stem cell accompanying loss of tissue and organ
regeneration potentials. Previously, we demonstrated that the life span of ovariectomy …

Fibrodysplasia ossificans progressiva is a rare genetic disorder characterized by
progressive heterotopic ossification. FOP patients develop soft tissue lumps as a result of …