[HTML][HTML] Endothelial GLUTs and vascular biology

WZ Wu, YP Bai - Biomedicine & pharmacotherapy, 2023 - Elsevier
Endothelial metabolism is a promising target for vascular functional regulation and disease
therapy. Glucose is the primary fuel for endothelial metabolism, supporting ATP generation …

[HTML][HTML] The role of FAK in tumor metabolism and therapy

J Zhang, SN Hochwald - Pharmacology & therapeutics, 2014 - Elsevier
Focal adhesion kinase (FAK) plays a vital role in tumor cell proliferation, survival and
migration. Altered metabolic pathways fuel rapid tumor growth by accelerating glucose, lipid …

Reactive oxygen species-driven HIF1α triggers accelerated glycolysis in endothelial cells exposed to low oxygen tension

JY Paik, KH Jung, JH Lee, JW Park, KH Lee - Nuclear Medicine and …, 2017 - Elsevier
Endothelial cells and their metabolic state regulate glucose transport into underlying tissues.
Here, we show that low oxygen tension stimulates human umbilical vein endothelial cell 18 …

[HTML][HTML] Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis

H Zhang, X Teng, Z Liu, L Zhang, Z Liu - Journal of Experimental & Clinical …, 2015 - Springer
Background To detect genetic expression profile alterations after papillary thyroid carcinoma
(PTC) cells transfected with chemokine receptor CXCR7 gene by gene microarray, and gain …

Nanoarchitecture of scaffolds and endothelial cells in engineering small diameter vascular grafts

KK Sankaran, A Subramanian… - Biotechnology …, 2015 - Wiley Online Library
Regeneration of functional small diameter blood vessels still remains a challenge, as the
synthetic vascular grafts fail to mimic the complex structural architecture and dynamic …

[HTML][HTML] Insights into bone marrow niche stability: an adhesion and metabolism route

D Ashok, L Polcik, S Dannewitz Prosseda… - Frontiers in Cell and …, 2022 - frontiersin.org
The bone marrow microenvironment provides critical cues for hematopoietic stem cell (HSC)
self-renewal and differentiation and contributes to their malignant conversion. The …

Neuron-derived neurotrophic factor ameliorates adverse cardiac remodeling after experimental myocardial infarction

Y Joki, K Ohashi, D Yuasa, R Shibata… - Circulation: Heart …, 2015 - Am Heart Assoc
Background—Myocardial infarction (MI) is one of the major causes of death worldwide.
Chronic heart failure is a serious complication of MI that leads to poor prognosis. We …

Loss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans

VA de Jesus Perez, K Yuan, ME Orcholski… - Circulation …, 2012 - Am Heart Assoc
Rationale: Pulmonary hypertension (PH) is characterized by progressive elevation in
pulmonary pressure and loss of small pulmonary arteries. As bone morphogenetic proteins …

[HTML][HTML] Integrated characterization of microRNA and mRNA transcriptome in papillary thyroid carcinoma

A Mohamad Yusof, R Jamal, R Muhammad… - Frontiers in …, 2018 - frontiersin.org
The incidence rate of papillary thyroid carcinoma (PTC) has rapidly increased in the recent
decades, and the microRNA (miRNA) is one of the potential biomarkers in this cancer …

FDG PET imaging and cardiovascular inflammation

N Hiari, JHF Rudd - Current cardiology reports, 2011 - Springer
The underlying pathologic mechanism of most acute coronary syndromes is atherosclerotic
plaque rupture. One cause of rupture is plaque inflammation, leading to fibrous cap …