Molecular nanomedicine towards cancer: 111In-labeled nanoparticles

D Psimadas, P Georgoulias, V Valotassiou… - Journal of …, 2012 - Elsevier
Nanomedicine is the medical application of materials, devices, or systems in the nanometer
scale and is currently undergoing explosive development. Molecular imaging of cancer …

Recent in vivo advances in cell-penetrating peptide-assisted drug delivery

K Kurrikoff, M Gestin, Ü Langel - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Delivery of macromolecular drugs is an important field in medical research.
However, macromolecules are usually unable to cross the cell membrane without the …

[HTML][HTML] Nanotargeted radionuclides for cancer nuclear imaging and internal radiotherapy

G Ting, CH Chang, HE Wang, TW Lee - BioMed Research …, 2010 - hindawi.com
Current progress in nanomedicine has exploited the possibility of designing tumor-targeted
nanocarriers being able to deliver radionuclide payloads in a site or molecular selective …

Targeting the nucleus: an overview of Auger-electron radionuclide therapy

B Cornelissen, KA Vallis - Current drug discovery technologies, 2010 - ingentaconnect.com
The review presented here lays out the present state of the art in the field of radionuclide
therapies specifically targeted against the nucleus of cancer cells, focussing on the use of …

Delivery of therapeutic radioisotopes using nanoparticle platforms: potential benefit in systemic radiation therapy

L Zhang, H Chen, L Wang, T Liu, J Yeh… - Nanotechnology …, 2010 - Taylor & Francis
Radiation therapy is an effective cancer treatment option in conjunction with chemotherapy
and surgery. Emerging individualized internal and systemic radiation treatment promises …

[HTML][HTML] Nanostructures as radionuclide carriers in auger electron therapy

NA Gharibkandi, J Gierałtowska, K Wawrowicz… - Materials, 2022 - mdpi.com
The concept of nanoparticle-mediated radionuclide delivery in the cancer treatment has
been widely discussed in the past decade. In particular, the use of inorganic and organic …

[HTML][HTML] Nano Yttrium-90 and Rhenium-188 production through medium medical cyclotron and research reactor for therapeutic usages: A Simulation study

A Khorshidi - Nuclear Engineering and Technology, 2023 - Elsevier
The main goal of the coordinated project development of therapeutic radiopharmaceuticals
of Y-90 and Re-188 is to exploit advancements in radionuclide production technology. Here …

Radiolabeled oligonucleotides targeting the RNA subunit of telomerase inhibit telomerase and induce DNA damage in telomerase-positive cancer cells

MR Jackson, BM Bavelaar, PA Waghorn, MR Gill… - Cancer research, 2019 - AACR
Telomerase is expressed in the majority (> 85%) of tumors, but has restricted expression in
normal tissues. Long-term telomerase inhibition in malignant cells results in progressive …

Radionanotheranostics for breast cancer diagnosis and therapy: Recent advances and future opportunities

AK Mehata, MK Viswanadh, VR Solomon… - … Nanomedicine for Breast …, 2022 - Elsevier
Breast cancer is one of the highest causes of mortality in women globally. Poor tumor
permeability, multidrug resistance, delayed diagnosis, and complications associated with …

Multimodality nuclear and fluorescence tumor imaging in mice using a streptavidin nanoparticle

M Liang, X Liu, D Cheng, G Liu, S Dou… - Bioconjugate …, 2010 - ACS Publications
Combining two or more different imaging modalities in the same agent can be of
considerable value in molecular imaging. We describe the use of streptavidin nanoparticle …