Assessing the interactions between radiotherapy and antitumour immunity

C Grassberger, SG Ellsworth, MQ Wilks… - Nature reviews Clinical …, 2019 - nature.com
Immunotherapy, specifically the introduction of immune checkpoint inhibitors, has
transformed the treatment of cancer, enabling long-term tumour control even in individuals …

PET imaging of inflammation in atherosclerosis

JM Tarkin, FR Joshi, JHF Rudd - Nature Reviews Cardiology, 2014 - nature.com
PET imaging of atherosclerosis can quantify several in vivo pathological processes
occurring within the arterial system. 18F-fluorodeoxyglucose (FDG) is the most-commonly …

[HTML][HTML] 18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial

NV Joshi, AT Vesey, MC Williams, ASV Shah… - The Lancet, 2014 - thelancet.com
Background The use of non-invasive imaging to identify ruptured or high-risk coronary
atherosclerotic plaques would represent a major clinical advance for prevention and …

[HTML][HTML] Joint SNMMI–ASNC expert consensus document on the role of 18F-FDG PET/CT in cardiac sarcoid detection and therapy monitoring

P Chareonthaitawee, RS Beanlands, W Chen… - 2017 - Springer
Background Sarcoidosis is a systemic disease characterized by significant clinical
heterogeneity. Although most frequently involving the lungs, sarcoidosis may affect any …

Coronary arterial 18F-sodium fluoride uptake: a novel marker of plaque biology

MR Dweck, MWL Chow, NV Joshi, MC Williams… - Journal of the American …, 2012 - jacc.org
Objectives: With combined positron emission tomography and computed tomography (CT),
we investigated coronary arterial uptake of 18F-sodium fluoride (18F-NaF) and 18F …

Imaging atherosclerosis

JM Tarkin, MR Dweck, NR Evans, RAP Takx… - Circulation …, 2016 - Am Heart Assoc
Advances in atherosclerosis imaging technology and research have provided a range of
diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular …

Assessment of valvular calcification and inflammation by positron emission tomography in patients with aortic stenosis

MR Dweck, C Jones, NV Joshi, AM Fletcher… - Circulation, 2012 - Am Heart Assoc
Background—The pathophysiology of aortic stenosis is incompletely understood, and the
relative contributions of valvular calcification and inflammation to disease progression are …

PET/MRI of inflammation in myocardial infarction

WW Lee, B Marinelli, AM Van Der Laan… - Journal of the American …, 2012 - jacc.org
Objectives: The aim of this study was to explore post–myocardial infarction (MI) myocardial
inflammation. Background: Innate immune cells are centrally involved in infarct healing and …

Patient preparation for cardiac fluorine-18 fluorodeoxyglucose positron emission tomography imaging of inflammation

MT Osborne, EA Hulten, VL Murthy, H Skali… - Journal of Nuclear …, 2017 - Elsevier
Although the number of clinical applications for fluorine-18 fluorodeoxyglucose (18 F-FDG)
cardiac positron emission tomography (PET) has continued to grow, there remains a lack of …

[HTML][HTML] 18F-NaF and 18F-FDG as molecular probes in the evaluation of atherosclerosis

ML McKenney-Drake, MC Moghbel, K Paydary… - European journal of …, 2018 - Springer
The early detection of atherosclerotic disease is vital to the effective prevention and
management of life-threatening cardiovascular events such as myocardial infarctions and …