Managing radiation use in medical imaging: a multifaceted challenge

H Hricak, DJ Brenner, SJ Adelstein, DP Frush, EJ Hall… - Radiology, 2011 - pubs.rsna.org
This special report aims to inform the medical community about the many challenges
involved in managing radiation exposure in a way that maximizes the benefit-risk ratio. The …

MIRD pamphlet no. 22 (abridged): radiobiology and dosimetry of α-particle emitters for targeted radionuclide therapy

G Sgouros, JC Roeske, MR McDevitt… - Journal of nuclear …, 2010 - Soc Nuclear Med
The potential of α-particle emitters to treat cancer has been recognized since the early
1900s. Advances in the targeted delivery of radionuclides and radionuclide conjugation …

Dosimetry, radiobiology and synthetic lethality: radiopharmaceutical therapy (RPT) with alpha-particle-emitters

G Sgouros - Seminars in nuclear medicine, 2020 - Elsevier
As a treatment modality that is fundamentally different from other therapies against cancer,
radiopharmaceutical therapy with alpha-particle emitters has drawn the attention of the …

Appropriate use of effective dose in radiation protection and risk assessment

DR Fisher, FH Fahey - Health physics, 2017 - journals.lww.com
Effective dose was introduced by the ICRP for the single, over-arching purpose of setting
limits for radiation protection. Effective dose is a derived quantity or mathematical construct …

Bioeffect modeling and equieffective dose concepts in radiation oncology–terminology, quantities and units

SM Bentzen, W Dörr, R Gahbauer, RW Howell… - Radiotherapy and …, 2012 - Elsevier
The International Commission on Radiation Units and Measurements (ICRU) Report
Committee on “Bioeffect Modeling and Biologically Equivalent Dose Concepts in Radiation …

FZD10‐targeted α‐radioimmunotherapy with 225Ac‐labeled OTSA101 achieves complete remission in a synovial sarcoma model

H Sudo, AB Tsuji, A Sugyo, Y Harada… - Cancer …, 2022 - Wiley Online Library
Synovial sarcomas are rare tumors arising in adolescents and young adults. The prognosis
for advanced disease is poor, with an overall survival of 12‐18 months. Frizzled homolog 10 …

[HTML][HTML] Treatment planning in molecular radiotherapy

G Glatting, M Bardiès, M Lassmann - Zeitschrift für Medizinische Physik, 2013 - Elsevier
In molecular radiotherapy a radionuclide or a radioactively labelled pharmaceutical is
administered to the patient. Treatment planning therefore comprises the determination of …

Structural changes and enzymatic hydrolysis yield of rice bran fiber under electron beam irradiation

T Li, L Wang, Z Chen, C Li, X Li, D Sun - Food and bioproducts processing, 2020 - Elsevier
The enzymatic hydrolysis yield of rice bran fiber (RBF) was enhanced by the electron beam
irradiation (EBI) pretreatment. Furthermore, the compositional analysis, structural changes …

[HTML][HTML] Targeted Alpha Therapy in mCRPC (Metastatic Castration-Resistant Prostate Cancer) Patients: Predictive Dosimetry and Toxicity Modeling of 225Ac-PSMA …

ML Belli, A Sarnelli, E Mezzenga, F Cesarini… - Frontiers in …, 2020 - frontiersin.org
Radioligand therapy is a type of internal radiotherapy combining a short-range radioisotope
labeled to a carrier with a high affinity for a specific receptor expressed on tumor cells …

Modelling and dosimetry for alpha-particle therapy

G Sgouros, RF Hobbs, H Song - Current radiopharmaceuticals, 2011 - ingentaconnect.com
As a consequence of the high potency and short range of alpha-particles,
radiopharmaceutical therapy with alpha-particle emitting radionuclides is a promising …