Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development

EG Solon, A Schweitzer, M Stoeckli, B Prideaux - The AAPS journal, 2010 - Springer
Abstract Whole-body autoradiography ((WBA) or quantitative WBA (QWBA)),
microautoradiography (MARG), matrix-assisted laser desorption/ionization mass …

[HTML][HTML] Cancer-associated fibroblasts enhance tumor 18F-FDG uptake and contribute to the intratumor heterogeneity of PET-CT

C Shangguan, G Gan, J Zhang, J Wu, Y Miao… - Theranostics, 2018 - ncbi.nlm.nih.gov
Purpose: Elevated glucose uptake is a hallmark of cancer. Fluorodeoxyglucose (FDG)
uptake was believed to indicate the aggressiveness of tumors and the standardized uptake …

A review of the toxicology and pathology of the gastrointestinal tract

GR Betton - Cell biology and toxicology, 2013 - Springer
The gastrointestinal tract of man and animals shows great specialization in structure and
function for its primary role of digestion. There are many species differences in diet, anatomy …

[HTML][HTML] Metabolic reprogramming of cancer-associated fibroblasts in pancreatic cancer contributes to the intratumor heterogeneity of PET-CT

Q Meng, Z Fang, X Mao, R Tang, C Liang, J Hua… - Computational and …, 2023 - Elsevier
Intratumor heterogeneity of positron emission tomography-computed tomography (PET-CT)
is reflected by variable 18 F-fluorodeoxyglucose (FDG) uptake. Increasing evidence has …

Detection of early stage atherosclerotic plaques using PET and CT fusion imaging targeting P-selectin in low density lipoprotein receptor-deficient mice

I Nakamura, K Hasegawa, Y Wada, T Hirase… - Biochemical and …, 2013 - Elsevier
BACKGROUND: Sensitive detection and qualitative analysis of atherosclerotic plaques are
in high demand in cardiovascular clinical settings. The leukocyte–endothelial interaction …

PET imaging analysis with 64Cu in disulfiram treatment for aberrant copper biodistribution in Menkes disease mouse model

S Nomura, S Nozaki, T Hamazaki… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Menkes disease (MD), an X-linked recessive disorder of copper metabolism caused by
mutations in the copper-transporting ATP7A gene, results in growth failure and severe …

[HTML][HTML] Involvement of cancer-derived EMT cells in the accumulation of 18F-fluorodeoxyglucose in the hypoxic cancer microenvironment

S Sugita, M Yamato, T Hatabu, Y Kataoka - Scientific reports, 2021 - nature.com
A high rate of glycolysis, one of the most common features of cancer, is used in positron
emission tomography (PET) imaging to visualize tumor tissues using 18F …

The Influence of Ethanolic Root Extracts of Ruellia tuberosa L. on Pancreatic Protease Activity and MDA Level of Rats (Rattus norvegicus) Induced by MLD-STZ

A Roosdiana, Sutrisno, C Mahdi… - IOP Conference Series …, 2019 - iopscience.iop.org
Diabetes mellitus (DM) is a metabolism disorder, indicated by increasing of blood glucose
levels, due to lack of insulin secretion or insulin resistance. This study aimed to determine …

[HTML][HTML] [18F]FDG Uptake in the Aortic Wall Smooth Muscle of Atherosclerotic Plaques in the Simian Atherosclerosis Model

T Iwaki, H Mizuma, K Hokamura, H Onoe… - BioMed Research …, 2016 - hindawi.com
Atherosclerosis is a self-sustaining inflammatory fibroproliferative disease that progresses in
discrete stages and involves a number of cell types and effector molecules. Recently,[18 F] …

Role of 18F-fluorodeoxyglucose Positron Emission Tomography in the Monitoring of Inflammatory Activity in Crohn's Disease

EA Russo, S Khan, R Janisch, RN Gunn… - Inflammatory bowel …, 2016 - academic.oup.com
Background 18Fluorine-fluorodeoxyglucose positron emission tomography (18F-FDG PET)
has recently attracted interest for the measurement of disease activity in Crohn's disease …