Current status of radiopharmaceutical therapy
In radiopharmaceutical therapy (RPT), a radionuclide is systemically or locally delivered with
the goal of targeting and delivering radiation to cancer cells while minimizing radiation …
the goal of targeting and delivering radiation to cancer cells while minimizing radiation …
Principles of nuclear medicine imaging: planar, SPECT, PET, multi-modality, and autoradiography systems
P Zanzonico - Radiation research, 2012 - meridian.allenpress.com
The underlying principles of nuclear medicine imaging involve the use of unsealed sources
of radioactivity in the form of radiopharmaceuticals. The ionizing radiations that accompany …
of radioactivity in the form of radiopharmaceuticals. The ionizing radiations that accompany …
89Zr-DFO-J591 for immunoPET of prostate-specific membrane antigen expression in vivo
JP Holland, V Divilov, NH Bander… - Journal of Nuclear …, 2010 - Soc Nuclear Med
89Zr (half-life, 78.41 h) is a positron-emitting radionuclide that displays excellent potential for
use in the design and synthesis of radioimmunoconjugates for immunoPET. In the current …
use in the design and synthesis of radioimmunoconjugates for immunoPET. In the current …
Standardized methods for the production of high specific-activity zirconium-89
JP Holland, Y Sheh, JS Lewis - Nuclear medicine and biology, 2009 - Elsevier
Zirconium-89 is an attractive metallo-radionuclide for use in immuno-PET due to favorable
decay characteristics. Standardized methods for the routine production and isolation of high …
decay characteristics. Standardized methods for the routine production and isolation of high …
Cerenkov luminescence imaging of medical isotopes
A Ruggiero, JP Holland, JS Lewis… - Journal of Nuclear …, 2010 - Soc Nuclear Med
The development of novel multimodality imaging agents and techniques represents the
current frontier of research in the field of medical imaging science. However, the …
current frontier of research in the field of medical imaging science. However, the …
First-in-human dosimetry of gastrin-releasing peptide receptor antagonist [177Lu]Lu-RM2: a radiopharmaceutical for the treatment of metastatic castration-resistant …
J Kurth, BJ Krause, SM Schwarzenböck… - European journal of …, 2020 - Springer
Purpose Besides PSMA, prostate cancer cells also express gastrin-releasing peptide
receptor (GRPr) which is therefore a promising target for theranostic approaches. The high …
receptor (GRPr) which is therefore a promising target for theranostic approaches. The high …
Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand diels–alder click chemistry
BM Zeglis, P Mohindra, GI Weissmann… - Bioconjugate …, 2011 - ACS Publications
A modular system for the construction of radiometalated antibodies was developed based
on the bioorthogonal cycloaddition reaction between 3-(4-benzylamino)-1, 2, 4, 5-tetrazine …
on the bioorthogonal cycloaddition reaction between 3-(4-benzylamino)-1, 2, 4, 5-tetrazine …
[HTML][HTML] Chelate-free metal ion binding and heat-induced radiolabeling of iron oxide nanoparticles
A novel reaction for chelate-free, heat-induced metal ion binding and radiolabeling of ultra-
small paramagnetic iron oxide nanoparticles (USPIOs) has been established …
small paramagnetic iron oxide nanoparticles (USPIOs) has been established …
Routine quality control recommendations for nuclear medicine instrumentation
EANM Physics Committee:… - European journal of …, 2010 - Springer
On behalf of the EANM Physics Committee: Ellinor Busemann Sokole & Anna Płachcínska &
Alan Britten With contribution from the EANM Working Group on Nuclear Medicine …
Alan Britten With contribution from the EANM Working Group on Nuclear Medicine …
[HTML][HTML] Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using 89Zr-DFO-Trastuzumab
JP Holland, E Caldas-Lopes, V Divilov, VA Longo… - PloS one, 2010 - journals.plos.org
Background The positron-emitting radionuclide 89Zr (t 1/2= 3.17 days) was used to prepare
89Zr-radiolabeled trastuzumab for use as a radiotracer for characterizing HER2/neu-positive …
89Zr-radiolabeled trastuzumab for use as a radiotracer for characterizing HER2/neu-positive …