Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety
of organisms including humans and, so far, hundreds of these structures have been isolated …

Prosthetic joint replacement surgery is performed with increasing frequency. Overall the
incidence of prosthetic joint infection (PJI) and subsequently prosthesis revision failure is …

Bacterial infections remain a major threat to humanity and are a leading cause of death and
disability. Antimicrobial resistance has been declared as one of the top ten threats to human …

Background Ubiquicidin is a peptide fragment with selective binding to negatively charged
bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it …

Nuclear medicine imaging techniques offer whole body imaging for localization of number
and site of infective foci inspite of limitation of spatial resolution. The innate human immune …

When serious infections are suspected, patients are often treated empirically with broad-
spectrum antibiotics while awaiting results that provide information on the bacterial class …

Timely and specific diagnosis of infectious diseases can be clinically challenging but
essential for the patient's outcome. Laboratory tests, such as a blood culture or urine …

Diabetic Foot Infections (DFIs) are associated with increased morbidity, an economic burden
on patients, their families and healthcare systems and increased mortality. Early diagnosis …

BACKGROUND: Previous studies demonstrated that 99mTc-labeled-ubiquicidin 29–41
(99mTc-UBI 29–41) imaging is an accurate method for detection of bacterial infections. This …

In nuclear medicine, the detection of inflamed and infected lesions is of growing interest.
Extensive efforts have been made to develop radiopharmaceuticals specific for inflammation …