[HTML][HTML] Antimicrobial peptides: their role as infection-selective tracers for molecular imaging
Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety
of organisms including humans and, so far, hundreds of these structures have been isolated …
of organisms including humans and, so far, hundreds of these structures have been isolated …
Prosthetic joint infections: radionuclide state-of-the-art imaging
F Gemmel, H Van den Wyngaert, C Love… - European journal of …, 2012 - Springer
Prosthetic joint replacement surgery is performed with increasing frequency. Overall the
incidence of prosthetic joint infection (PJI) and subsequently prosthesis revision failure is …
incidence of prosthetic joint infection (PJI) and subsequently prosthesis revision failure is …
Radiotracer development for bacterial imaging
Bacterial infections remain a major threat to humanity and are a leading cause of death and
disability. Antimicrobial resistance has been declared as one of the top ten threats to human …
disability. Antimicrobial resistance has been declared as one of the top ten threats to human …
A decade of ubiquicidin development for PET imaging of infection: A systematic review
B Marjanovic-Painter, J Kleynhans, JR Zeevaart… - Nuclear Medicine and …, 2023 - Elsevier
Background Ubiquicidin is a peptide fragment with selective binding to negatively charged
bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it …
bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it …
[HTML][HTML] Antimicrobial peptides as infection imaging agents: better than radiolabeled antibiotics
Nuclear medicine imaging techniques offer whole body imaging for localization of number
and site of infective foci inspite of limitation of spatial resolution. The innate human immune …
and site of infective foci inspite of limitation of spatial resolution. The innate human immune …
Pathogen-specific bacterial imaging in nuclear medicine
AA Ordonez, SK Jain - Seminars in nuclear medicine, 2018 - Elsevier
When serious infections are suspected, patients are often treated empirically with broad-
spectrum antibiotics while awaiting results that provide information on the bacterial class …
spectrum antibiotics while awaiting results that provide information on the bacterial class …
Future diagnostic agents
F Gemmel, N Dumarey, M Welling - Seminars in nuclear medicine, 2009 - Elsevier
Timely and specific diagnosis of infectious diseases can be clinically challenging but
essential for the patient's outcome. Laboratory tests, such as a blood culture or urine …
essential for the patient's outcome. Laboratory tests, such as a blood culture or urine …
New imaging tracers for the infected diabetic foot (nuclear and optical imaging)
AO Ankrah, HC Klein, PH Elsinga - Current Pharmaceutical …, 2018 - ingentaconnect.com
Diabetic Foot Infections (DFIs) are associated with increased morbidity, an economic burden
on patients, their families and healthcare systems and increased mortality. Early diagnosis …
on patients, their families and healthcare systems and increased mortality. Early diagnosis …
Clinical utility of 99mTc-labeled ubiquicidin 29–41 antimicrobial peptide for the scintigraphic detection of mediastinitis after cardiac surgery
E Vallejo, I Martinez, A Tejero, S Hernandez… - Archives of medical …, 2008 - Elsevier
BACKGROUND: Previous studies demonstrated that 99mTc-labeled-ubiquicidin 29–41
(99mTc-UBI 29–41) imaging is an accurate method for detection of bacterial infections. This …
(99mTc-UBI 29–41) imaging is an accurate method for detection of bacterial infections. This …
Technetium-99m based small molecule radiopharmaceuticals and radiotracers targeting inflammation and infection
T Kniess, M Laube, F Wüst, J Pietzsch - Dalton transactions, 2017 - pubs.rsc.org
In nuclear medicine, the detection of inflamed and infected lesions is of growing interest.
Extensive efforts have been made to develop radiopharmaceuticals specific for inflammation …
Extensive efforts have been made to develop radiopharmaceuticals specific for inflammation …